Cyclin-Dependent Kinase 8

"Cyclin-Dependent Kinase 8" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A CYCLIN C dependent kinase that is an important component of the mediator complex. The enzyme is activated by its interaction with CYCLIN C and plays a role in transcriptional regulation by phosphorylating RNA POLYMERASE II.

Descriptor ID	D056850
MeSH Number(s)	D05.500.374.500 D08.811.913.696.620.682.700.646.500.968 D12.644.360.024.309.500 D12.644.360.250.547 D12.776.157.057.072.500 D12.776.167.200.548 D12.776.476.024.388.500 D12.776.476.250.548 D12.776.660.551.500
Concept/Terms	Cyclin-Dependent Kinase 8 Cyclin-Dependent Kinase 8 Cyclin Dependent Kinase 8 Cdk8 Cyclin-Dependent Kinase Cdk8 Cyclin Dependent Kinase Cyclin-Dependent Kinase, Cdk8 Kinase, Cdk8 Cyclin-Dependent Cdk8 Protein Kinase Kinase, Cdk8 Protein Protein Kinase, Cdk8 Cell Division Protein Kinase 8

Below are MeSH descriptors whose meaning is more general than "Cyclin-Dependent Kinase 8".

Chemicals and Drugs [D]
Macromolecular Substances [D05]
Multiprotein Complexes [D05.500]
Mediator Complex [D05.500.374]
Cyclin-Dependent Kinase 8 [D05.500.374.500]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
Phosphotransferases [D08.811.913.696]
Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
Protein Kinases [D08.811.913.696.620.682]
Protein-Serine-Threonine Kinases [D08.811.913.696.620.682.700]
Proline-Directed Protein Kinases [D08.811.913.696.620.682.700.646]
Cyclin-Dependent Kinases [D08.811.913.696.620.682.700.646.500]
Cyclin-Dependent Kinase 8 [D08.811.913.696.620.682.700.646.500.968]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Adaptor Proteins, Signal Transducing [D12.644.360.024]
Mediator Complex [D12.644.360.024.309]
Cyclin-Dependent Kinase 8 [D12.644.360.024.309.500]
Cyclin-Dependent Kinases [D12.644.360.250]
Cyclin-Dependent Kinase 8 [D12.644.360.250.547]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
Adaptor Proteins, Signal Transducing [D12.776.157.057]
Mediator Complex [D12.776.157.057.072]
Cyclin-Dependent Kinase 8 [D12.776.157.057.072.500]
Cell Cycle Proteins [D12.776.167]
Cyclin-Dependent Kinases [D12.776.167.200]
Cyclin-Dependent Kinase 8 [D12.776.167.200.548]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Adaptor Proteins, Signal Transducing [D12.776.476.024]
Mediator Complex [D12.776.476.024.388]
Cyclin-Dependent Kinase 8 [D12.776.476.024.388.500]
Cyclin-Dependent Kinases [D12.776.476.250]
Cyclin-Dependent Kinase 8 [D12.776.476.250.548]
Nuclear Proteins [D12.776.660]
Mediator Complex [D12.776.660.551]
Cyclin-Dependent Kinase 8 [D12.776.660.551.500]

Below are MeSH descriptors whose meaning is related to "Cyclin-Dependent Kinase 8".

Below are MeSH descriptors whose meaning is more specific than "Cyclin-Dependent Kinase 8".

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