SKP Cullin F-Box Protein Ligases
"SKP Cullin F-Box Protein Ligases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subset of ubiquitin protein ligases that are formed by the association of a SKP DOMAIN PROTEIN, a CULLIN DOMAIN PROTEIN and a F-BOX DOMAIN PROTEIN.
| Descriptor ID |
D044843
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| MeSH Number(s) |
D08.811.464.938.750.750
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| Concept/Terms |
SKP1-Cullin Ubiquitin Ligases- SKP1-Cullin Ubiquitin Ligases
- Ligases, SKP1-Cullin Ubiquitin
- SKP1 Cullin Ubiquitin Ligases
- Ubiquitin Ligases, SKP1-Cullin
- Skp1-Cullin-1-F-box Ubiquitin Ligase
- Ligase, Skp1-Cullin-1-F-box Ubiquitin
- Skp1 Cullin 1 F box Ubiquitin Ligase
- Ubiquitin Ligase, Skp1-Cullin-1-F-box
- Skp1-Cullin-F-Box Proteins
- Skp1 Cullin F Box Proteins
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Below are MeSH descriptors whose meaning is more general than "SKP Cullin F-Box Protein Ligases".
Below are MeSH descriptors whose meaning is more specific than "SKP Cullin F-Box Protein Ligases".
This graph shows the total number of publications written about "SKP Cullin F-Box Protein Ligases" by people in this website by year, and whether "SKP Cullin F-Box Protein Ligases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 2 | 0 | 2 |
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Below are the most recent publications written about "SKP Cullin F-Box Protein Ligases" by people in Profiles.
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Fukushima H, Ogura K, Wan L, Lu Y, Li V, Gao D, Liu P, Lau AW, Wu T, Kirschner MW, Inuzuka H, Wei W. SCF-mediated Cdh1 degradation defines a negative feedback system that coordinates cell-cycle progression. Cell Rep. 2013 Aug 29; 4(4):803-16.
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Lau AW, Inuzuka H, Fukushima H, Wan L, Liu P, Gao D, Sun Y, Wei W. Regulation of APC(Cdh1) E3 ligase activity by the Fbw7/cyclin E signaling axis contributes to the tumor suppressor function of Fbw7. Cell Res. 2013 Jul; 23(7):947-61.
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Inuzuka H, Shaik S, Onoyama I, Gao D, Tseng A, Maser RS, Zhai B, Wan L, Gutierrez A, Lau AW, Xiao Y, Christie AL, Aster J, Settleman J, Gygi SP, Kung AL, Look T, Nakayama KI, DePinho RA, Wei W. SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction. Nature. 2011 Mar 03; 471(7336):104-9.
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Lin HK, Chen Z, Wang G, Nardella C, Lee SW, Chan CH, Chan CH, Yang WL, Wang J, Egia A, Nakayama KI, Cordon-Cardo C, Teruya-Feldstein J, Pandolfi PP. Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. Nature. 2010 Mar 18; 464(7287):374-9.
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Lin HK, Wang G, Chen Z, Teruya-Feldstein J, Liu Y, Chan CH, Yang WL, Erdjument-Bromage H, Nakayama KI, Nimer S, Tempst P, Pandolfi PP. Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB. Nat Cell Biol. 2009 Apr; 11(4):420-32.
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Noubissi FK, Elcheva I, Bhatia N, Shakoori A, Ougolkov A, Liu J, Minamoto T, Ross J, Fuchs SY, Spiegelman VS. CRD-BP mediates stabilization of betaTrCP1 and c-myc mRNA in response to beta-catenin signalling. Nature. 2006 Jun 15; 441(7095):898-901.