"Connexins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of homologous proteins which form the intermembrane channels of GAP JUNCTIONS. The connexins are the products of an identified gene family which has both highly conserved and highly divergent regions. The variety contributes to the wide range of functional properties of gap junctions.
| Descriptor ID |
D017630
|
| MeSH Number(s) |
D12.776.543.585.250
|
| Concept/Terms |
Connexins- Connexins
- Gap Junction Protein
- Junction Protein, Gap
- Gap Junction Proteins
- Junction Proteins, Gap
- Gap Junction Channel Proteins
|
Below are MeSH descriptors whose meaning is more general than "Connexins".
Below are MeSH descriptors whose meaning is more specific than "Connexins".
This graph shows the total number of publications written about "Connexins" by people in this website by year, and whether "Connexins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2004 | 3 | 0 | 3 |
| 2007 | 1 | 0 | 1 |
| 2012 | 3 | 0 | 3 |
| 2014 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Connexins" by people in Profiles.
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Jezzini SH, Merced A, Blagburn JM. Shaking-B misexpression increases the formation of gap junctions but not chemical synapses between auditory sensory neurons and the giant fiber of Drosophila melanogaster. PLoS One. 2018; 13(8):e0198710.
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P?zier AP, Jezzini SH, Bacon JP, Blagburn JM. Shaking B Mediates Synaptic Coupling between Auditory Sensory Neurons and the Giant Fiber of Drosophila melanogaster. PLoS One. 2016; 11(4):e0152211.
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Zolla V, Nizamutdinova IT, Scharf B, Clement CC, Maejima D, Akl T, Nagai T, Luciani P, Leroux JC, Halin C, Stukes S, Tiwari S, Casadevall A, Jacobs WR, Entenberg D, Zawieja DC, Condeelis J, Fooksman DR, Gashev AA, Santambrogio L. Aging-related anatomical and biochemical changes in lymphatic collectors impair lymph transport, fluid homeostasis, and pathogen clearance. Aging Cell. 2015 Aug; 14(4):582-94.
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Biswas SK, Brako L, Gu S, Jiang JX, Lo WK. Regional changes of AQP0-dependent square array junction and gap junction associated with cortical cataract formation in the Emory mutant mouse. Exp Eye Res. 2014 Oct; 127:132-42.
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Su V, Lau AF. Connexins: mechanisms regulating protein levels and intercellular communication. FEBS Lett. 2014 Apr 17; 588(8):1212-20.
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Su V, Cochrane K, Lau AF. Degradation of connexins through the proteasomal, endolysosomal and phagolysosomal pathways. J Membr Biol. 2012 Jul; 245(7):389-400.
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O'Brien JJ, Chen X, Macleish PR, O'Brien J, Massey SC. Photoreceptor coupling mediated by connexin36 in the primate retina. J Neurosci. 2012 Mar 28; 32(13):4675-87.
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Su V, Lau AF. Ubiquitination, intracellular trafficking, and degradation of connexins. Arch Biochem Biophys. 2012 Aug 01; 524(1):16-22.
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Moreno AP, Lau AF. Gap junction channel gating modulated through protein phosphorylation. Prog Biophys Mol Biol. 2007 May-Jun; 94(1-2):107-19.
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Chappell RL, Qian H, Zakevicius J, Ripps H. Histidine suppresses zinc modulation of connexin hemichannels. Biol Bull. 2004 Dec; 207(3):188-90.