"Carboxypeptidase H" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ZINC-containing exopeptidase primarily found in SECRETORY VESICLES of endocrine and neuroendocrine cells. It catalyzes the cleavage of C-terminal ARGININE or LYSINE residues from polypeptides and is active in processing precursors of PEPTIDE HORMONES and other bioactive peptides.
| Descriptor ID |
D043423
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| MeSH Number(s) |
D08.811.277.656.350.245.167 D08.811.277.656.350.555.250 D08.811.277.656.675.555.250 D08.811.277.656.837.124
|
| Concept/Terms |
Carboxypeptidase H- Carboxypeptidase H
- Enkephalin-Synthesizing Carboxypeptidase
- Carboxypeptidase, Enkephalin-Synthesizing
- Enkephalin Synthesizing Carboxypeptidase
- Enkephalin-Forming Carboxypeptidase
- Carboxypeptidase, Enkephalin-Forming
- Enkephalin Forming Carboxypeptidase
- Carboxypeptidase E
- Enkephalin Convertase
- Convertase, Enkephalin
|
Below are MeSH descriptors whose meaning is more general than "Carboxypeptidase H".
Below are MeSH descriptors whose meaning is more specific than "Carboxypeptidase H".
This graph shows the total number of publications written about "Carboxypeptidase H" by people in this website by year, and whether "Carboxypeptidase H" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Carboxypeptidase H" by people in Profiles.
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Xiao L, Chang SY, Xiong ZG, Selveraj P, Peng Loh Y. Absence of Carboxypeptidase E/Neurotrophic Factor-?1 in Knock-Out Mice Leads to Dysfunction of BDNF-TRKB Signaling in Hippocampus. J Mol Neurosci. 2017 May; 62(1):79-87.
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Woronowicz A, Cawley NX, Chang SY, Koshimizu H, Phillips AW, Xiong ZG, Loh YP. Carboxypeptidase E knockout mice exhibit abnormal dendritic arborization and spine morphology in central nervous system neurons. J Neurosci Res. 2010 Jan; 88(1):64-72.
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Woronowicz A, Koshimizu H, Chang SY, Cawley NX, Hill JM, Rodriguiz RM, Abebe D, Dorfman C, Senatorov V, Zhou A, Xiong ZG, Wetsel WC, Loh YP. Absence of carboxypeptidase E leads to adult hippocampal neuronal degeneration and memory deficits. Hippocampus. 2008; 18(10):1051-63.
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Zhou A, Minami M, Zhu X, Bae S, Minthorne J, Lan J, Xiong ZG, Simon RP. Altered biosynthesis of neuropeptide processing enzyme carboxypeptidase E after brain ischemia: molecular mechanism and implication. J Cereb Blood Flow Metab. 2004 Jun; 24(6):612-22.