"Renin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A highly specific (Leu-Leu) endopeptidase that generates ANGIOTENSIN I from its precursor ANGIOTENSINOGEN, leading to a cascade of reactions which elevate BLOOD PRESSURE and increase sodium retention by the kidney in the RENIN-ANGIOTENSIN SYSTEM. The enzyme was formerly listed as EC 3.4.99.19.
| Descriptor ID |
D012083
|
| MeSH Number(s) |
D08.811.277.656.074.500.780 D08.811.277.656.300.048.780 D08.811.277.656.837.750
|
| Concept/Terms |
Renin- Renin
- Angiotensin-Forming Enzyme
- Angiotensin Forming Enzyme
- Angiotensinogenase
Prorenin- Prorenin
- Inactive Renin
- Renin, Inactive
- Big Renin
- Renin, Big
- Cryorenin
|
Below are MeSH descriptors whose meaning is more general than "Renin".
Below are MeSH descriptors whose meaning is more specific than "Renin".
This graph shows the total number of publications written about "Renin" by people in this website by year, and whether "Renin" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 2 | 2 |
| 2005 | 1 | 1 | 2 |
| 2007 | 1 | 3 | 4 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 1 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 3 | 0 | 3 |
| 2014 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2020 | 1 | 1 | 2 |
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Below are the most recent publications written about "Renin" by people in Profiles.
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Adedapo AA, Osaretin ER, Falayi OO, Oyagbemi AA, Ogunpolu BS, Omobowale TO, Oguntibeju OO, Yakubu MA. Ramipril blunts glycerol-induced acute renal failure in rats through its antiapoptosis, anti-inflammatory, antioxidant, and renin-inhibiting properties. J Basic Clin Physiol Pharmacol. 2020 Nov 06; 32(3):225-235.
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Brown JM, Siddiqui M, Calhoun DA, Carey RM, Hopkins PN, Williams GH, Vaidya A. The Unrecognized Prevalence of Primary Aldosteronism: A Cross-sectional Study. Ann Intern Med. 2020 07 07; 173(1):10-20.
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Deng L, Xiong Z, Li H, Lei X, Cheng L. Analytical validation and investigation on reference intervals of aldosterone and renin in Chinese Han population by using fully automated chemiluminescence immunoassays. Clin Biochem. 2018 Jun; 56:89-94.
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Joseph JJ, Echouffo-Tcheugui JB, Kalyani RR, Yeh HC, Bertoni AG, Effoe VS, Casanova R, Sims M, Wu WC, Wand GS, Correa A, Golden SH. Aldosterone, Renin, Cardiovascular Events, and All-Cause Mortality Among African?Americans: The Jackson Heart Study. JACC Heart Fail. 2017 09; 5(9):642-651.
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Ghazi L, Oparil S, Calhoun DA, Lin CP, Dudenbostel T. Distinctive Risk Factors and Phenotype of Younger Patients With Resistant Hypertension: Age Is Relevant. Hypertension. 2017 05; 69(5):827-835.
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De Mello WC. Local Renin Angiotensin Aldosterone Systems and Cardiovascular Diseases. Med Clin North Am. 2017 Jan; 101(1):117-127.
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De Mello W. Intracellular renin increases the inward calcium current in smooth muscle cells of mesenteric artery of SHR. Implications for hypertension and vascular remodeling. Peptides. 2016 10; 84:36-43.
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De Mello WC. Intracellular angiotensin II as a regulator of muscle tone in vascular resistance vessels. Pathophysiological implications. Peptides. 2016 Apr; 78:87-90.
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Joseph JJ, Echouffo-Tcheugui JB, Kalyani RR, Yeh HC, Bertoni AG, Effoe VS, Casanova R, Sims M, Correa A, Wu WC, Wand GS, Golden SH. Aldosterone, Renin, and Diabetes Mellitus in African Americans: The Jackson Heart Study. J Clin Endocrinol Metab. 2016 04; 101(4):1770-8.
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Hoffmann P, Beckman D, McLean LA, Yan JH. Aliskiren toxicity in juvenile rats is determined by ontogenic regulation of intestinal P-glycoprotein expression. Toxicol Appl Pharmacol. 2014 Feb 15; 275(1):36-43.