Eukaryotic Initiation Factors
"Eukaryotic Initiation Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Peptide initiation factors from eukaryotic organisms. Over twelve factors are involved in PEPTIDE CHAIN INITIATION, TRANSLATIONAL in eukaryotic cells. Many of these factors play a role in controlling the rate of MRNA TRANSLATION.
| Descriptor ID |
D039642
|
| MeSH Number(s) |
D12.776.835.725.868
|
| Concept/Terms |
Eukaryotic Initiation Factors- Eukaryotic Initiation Factors
- Initiation Factors, Eukaryotic
- Translation Initiation Factors, Eukaryotic
- Eukaryotic Peptide Initiation Factors
- Peptide Initiation Factors, Eukaryotic
|
Below are MeSH descriptors whose meaning is more general than "Eukaryotic Initiation Factors".
Below are MeSH descriptors whose meaning is more specific than "Eukaryotic Initiation Factors".
This graph shows the total number of publications written about "Eukaryotic Initiation Factors" by people in this website by year, and whether "Eukaryotic Initiation Factors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2008 | 2 | 0 | 2 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 0 | 2 | 2 |
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Below are the most recent publications written about "Eukaryotic Initiation Factors" by people in Profiles.
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Khan MA, Goss DJ. Poly (A) binding protein enhances the binding affinity of potyvirus VPg to eukaryotic initiation factor eIF4F and activates in vitro translation. Int J Biol Macromol. 2019 Jan; 121:947-955.
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Liu Q, Goss DJ. The 3' mRNA I-shaped structure of maize necrotic streak virus binds to eukaryotic translation factors for eIF4F-mediated translation initiation. J Biol Chem. 2018 06 15; 293(24):9486-9495.
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Zhao P, Liu Q, Miller WA, Goss DJ. Eukaryotic translation initiation factor 4G (eIF4G) coordinates interactions with eIF4A, eIF4B, and eIF4E in binding and translation of the barley yellow dwarf virus 3' cap-independent translation element (BTE). J Biol Chem. 2017 04 07; 292(14):5921-5931.
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Zhou JW, Li Y, Yue LX, Luo CL, Chen Y, Zhang JY. Autoantibody response to Sui1 and its tissue-specific expression in hepatocellular carcinoma. Tumour Biol. 2016 Feb; 37(2):2547-53.
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Ma KL, Liu J, Wang CX, Ni J, Zhang Y, Wu Y, Lv LL, Ruan XZ, Liu BC. Activation of mTOR modulates SREBP-2 to induce foam cell formation through increased retinoblastoma protein phosphorylation. Cardiovasc Res. 2013 Dec 01; 100(3):450-60.
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Khan MA, Goss DJ. Poly(A)-binding protein increases the binding affinity and kinetic rates of interaction of viral protein linked to genome with translation initiation factors eIFiso4F and eIFiso4F?4B complex. Biochemistry. 2012 Feb 21; 51(7):1388-95.
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Yumak H, Khan MA, Goss DJ. Poly(A) tail affects equilibrium and thermodynamic behavior of tobacco etch virus mRNA with translation initiation factors eIF4F, eIF4B and PABP. Biochim Biophys Acta. 2010 Sep; 1799(9):653-8.
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Chen Y, Zhou Y, Qiu S, Wang K, Liu S, Peng XX, Li J, Tan EM, Zhang JY. Autoantibodies to tumor-associated antigens combined with abnormal alpha-fetoprotein enhance immunodiagnosis of hepatocellular carcinoma. Cancer Lett. 2010 Mar 01; 289(1):32-9.
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Cheng S, Sultana S, Goss DJ, Gallie DR. Translation initiation factor 4B homodimerization, RNA binding, and interaction with Poly(A)-binding protein are enhanced by zinc. J Biol Chem. 2008 Dec 26; 283(52):36140-53.
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Khan MA, Yumak H, Gallie DR, Goss DJ. Effects of poly(A)-binding protein on the interactions of translation initiation factor eIF4F and eIF4F.4B with internal ribosome entry site (IRES) of tobacco etch virus RNA. Biochim Biophys Acta. 2008 Oct; 1779(10):622-7.