Eukaryotic Initiation Factor-3
"Eukaryotic Initiation Factor-3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multisubunit eukaryotic initiation factor that contains at least 8 distinct polypeptides. It plays a role in recycling of ribosomal subunits to the site of transcription initiation by promoting the dissociation of non-translating ribosomal subunits. It also is involved in promoting the binding of a ternary complex of EUKARYOTIC INITIATION FACTOR-2; GTP; and INITIATOR TRNA to the 40S ribosomal subunit.
| Descriptor ID |
D039621
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| MeSH Number(s) |
D12.776.835.725.868.437
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| Concept/Terms |
Eukaryotic Initiation Factor-3- Eukaryotic Initiation Factor-3
- Eukaryotic Initiation Factor 3
- Initiation Factor-3, Eukaryotic
- Peptide Initiation Factor EIF-3
- Peptide Initiation Factor EIF 3
- Eukaryotic Peptide Initiation Factor-3
- Eukaryotic Peptide Initiation Factor 3
- EIF-3
- EIF3
Eukaryotic Initiation Factor-3, Subunit 2- Eukaryotic Initiation Factor-3, Subunit 2
- Eukaryotic Initiation Factor 3, Subunit 2
- Eukaryotic Initiation Factor-3, beta Subunit
- Eukaryotic Initiation Factor 3, beta Subunit
- Eukaryotic Peptide Initiation Factor-3, Subunit 2
- Eukaryotic Peptide Initiation Factor 3, Subunit 2
- EIF3-beta
Eukaryotic Initiation Factor-3, Subunit 3- Eukaryotic Initiation Factor-3, Subunit 3
- Eukaryotic Initiation Factor 3, Subunit 3
- Eukaryotic Peptide Initiation Factor-3, Subunit 3
- Eukaryotic Peptide Initiation Factor 3, Subunit 3
- EIF3S3 Protein
- Eukaryotic Initiation Factor-3, gamma Subunit
- Eukaryotic Initiation Factor 3, gamma Subunit
- EIF3-gamma
- EIF3 gamma
- EIF3S3 Gene Product
Eukaryotic Initiation Factor-3, Subunit 8- Eukaryotic Initiation Factor-3, Subunit 8
- Eukaryotic Initiation Factor 3, Subunit 8
- Eukaryotic Initiation Factor-3 p110
- Eukaryotic Initiation Factor 3 p110
- Eukaryotic Translation Initiation Factor-3, Subunit 8
- Eukaryotic Translation Initiation Factor 3, Subunit 8
- EIF3 p110
Eukaryotic Initiation Factor-3, Subunit 5- Eukaryotic Initiation Factor-3, Subunit 5
- Eukaryotic Initiation Factor 3, Subunit 5
- Eukaryotic Initiation Factor-3, delta Subunit
- Eukaryotic Initiation Factor 3, delta Subunit
- Eukaryotic Peptide Initiation Factor 3, Subunit 5
- EIF3-epsilon
- EIF3 epsilon
Eukaryotic Initiation Factor-3, Subunit 6- Eukaryotic Initiation Factor-3, Subunit 6
- Eukaryotic Initiation Factor 3, Subunit 6
- INT6 Protein
- Int-6 Protein
- Int 6 Protein
- EIF3-p48
- Int-6 Gene Product
- Gene Product, Int-6
- Int 6 Gene Product
Eukaryotic Initiation Factor-3, Subunit 7- Eukaryotic Initiation Factor-3, Subunit 7
- Eukaryotic Initiation Factor 3, Subunit 7
- Eukaryotic Initiation Factor-3, zeta Subunit
- Eukaryotic Initiation Factor 3, zeta Subunit
- EIF3-zeta
Eukaryotic Initiation Factor-3, Subunit 1- Eukaryotic Initiation Factor-3, Subunit 1
- Eukaryotic Initiation Factor 3, Subunit 1
- Eukaryotic Peptide Initiation Factor-3, alpha Subunit
- Eukaryotic Peptide Initiation Factor 3, alpha Subunit
- Eukaryotic Peptide Initiation Factor-3, Subunit 1
- Eukaryotic Peptide Initiation Factor 3, Subunit 1
- EIF3-alpha
- EIF3 alpha
Eukaryotic Initiation Factor-3, Subunit 4- Eukaryotic Initiation Factor-3, Subunit 4
- Eukaryotic Initiation Factor 3, Subunit 4
- p42 EIF3 Protein
- EIF3 Protein, p42
- Eukaryotic Peptide Initiation Factor-3, Subunit 4
- Eukaryotic Peptide Initiation Factor 3, Subunit 4
- EIF3 p42 Protein
- EIF3S4 Protein
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Below are MeSH descriptors whose meaning is more general than "Eukaryotic Initiation Factor-3".
Below are MeSH descriptors whose meaning is more specific than "Eukaryotic Initiation Factor-3".
This graph shows the total number of publications written about "Eukaryotic Initiation Factor-3" by people in this website by year, and whether "Eukaryotic Initiation Factor-3" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Eukaryotic Initiation Factor-3" by people in Profiles.
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Powell P, Bhardwaj U, Goss D. Eukaryotic initiation factor 4F promotes a reorientation of eukaryotic initiation factor 3 binding on the 5' and the 3' UTRs of barley yellow dwarf virus mRNA. Nucleic Acids Res. 2022 05 20; 50(9):4988-4999.
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Bhardwaj U, Powell P, Goss DJ. Eukaryotic initiation factor (eIF) 3 mediates Barley Yellow Dwarf Viral mRNA 3'-5' UTR interactions and 40S ribosomal subunit binding to facilitate cap-independent translation. Nucleic Acids Res. 2019 07 09; 47(12):6225-6235.
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Habeeb O, Goodglick L, Soslow RA, Rao RG, Gordon LK, Schirripa O, Horvath S, Braun J, Seligson DB, Wadehra M. Epithelial membrane protein-2 expression is an early predictor of endometrial cancer development. Cancer. 2010 Oct 15; 116(20):4718-26.
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Garcia-Barrio MT, Naranda T, Vazquez de Aldana CR, Cuesta R, Hinnebusch AG, Hershey JW, Tamame M. GCD10, a translational repressor of GCN4, is the RNA-binding subunit of eukaryotic translation initiation factor-3. Genes Dev. 1995 Jul 15; 9(14):1781-96.