"Integrin alpha1beta1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Integrin alpha1beta1 functions as a receptor for LAMININ and COLLAGEN. It is widely expressed during development, but in the adult is the predominant laminin receptor (RECEPTORS, LAMININ) in mature SMOOTH MUSCLE CELLS, where it is important for maintenance of the differentiated phenotype of these cells. Integrin alpha1beta1 is also found in LYMPHOCYTES and microvascular endothelial cells, and may play a role in angiogenesis. In SCHWANN CELLS and neural crest cells, it is involved in cell migration. Integrin alpha1beta1 is also known as VLA-1 and CD49a-CD29.
| Descriptor ID |
D039222
|
| MeSH Number(s) |
D12.776.543.750.685.100 D12.776.543.750.705.408.850.099 D12.776.543.750.705.876.249
|
| Concept/Terms |
Integrin alpha1beta1- Integrin alpha1beta1
- alpha1beta1, Integrin
- VLA-1
- Integrin alpha(1)beta(1)
- CD49a-CD29
- alpha1beta1 Integrin
- Integrin, alpha1beta1
|
Below are MeSH descriptors whose meaning is more general than "Integrin alpha1beta1".
Below are MeSH descriptors whose meaning is more specific than "Integrin alpha1beta1".
This graph shows the total number of publications written about "Integrin alpha1beta1" by people in this website by year, and whether "Integrin alpha1beta1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Integrin alpha1beta1" by people in Profiles.
-
Zent R, Yan X, Su Y, Hudson BG, Borza DB, Moeckel GW, Qi Z, Sado Y, Breyer MD, Voziyan P, Pozzi A. Glomerular injury is exacerbated in diabetic integrin alpha1-null mice. Kidney Int. 2006 Aug; 70(3):460-70.
-
Ochieng J, Leite-Browning ML, Warfield P. Regulation of cellular adhesion to extracellular matrix proteins by galectin-3. Biochem Biophys Res Commun. 1998 May 29; 246(3):788-91.