"Integrin alpha5beta1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An integrin found in FIBROBLASTS; PLATELETS; MONOCYTES, and LYMPHOCYTES. Integrin alpha5beta1 is the classical receptor for FIBRONECTIN, but it also functions as a receptor for LAMININ and several other EXTRACELLULAR MATRIX PROTEINS.
| Descriptor ID |
D039081
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| MeSH Number(s) |
D12.776.395.550.625.379 D12.776.543.550.625.379 D12.776.543.750.705.408.530.750 D12.776.543.750.705.408.850.349 D12.776.543.750.705.675.460 D12.776.543.750.705.876.374
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| Concept/Terms |
Integrin alpha5beta1- Integrin alpha5beta1
- alpha5beta1, Integrin
- Integrin alpha-5 beta-1
- Integrin alpha 5 beta 1
- alpha-5 beta-1, Integrin
- beta-1, Integrin alpha-5
- Platelet Glycoprotein Ic-IIa
- Glycoprotein Ic-IIa, Platelet
- Ic-IIa, Platelet Glycoprotein
- Platelet Glycoprotein Ic IIa
- VLA-5
- VLA-5 Receptors
- VLA 5 Receptors
- Fibronectin Receptor
- Receptor, Fibronectin
- Receptors, VLA-5
- Receptors, VLA 5
|
Below are MeSH descriptors whose meaning is more general than "Integrin alpha5beta1".
Below are MeSH descriptors whose meaning is more specific than "Integrin alpha5beta1".
This graph shows the total number of publications written about "Integrin alpha5beta1" by people in this website by year, and whether "Integrin alpha5beta1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Integrin alpha5beta1" by people in Profiles.
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Caliva MJ, Yang WS, Young-Robbins S, Zhou M, Yoon H, Matter ML, Grimes ML, Conrads T, Ramos JW. Proteomics analysis identifies PEA-15 as an endosomal phosphoprotein that regulates a5?1 integrin endocytosis. Sci Rep. 2021 10 06; 11(1):19830.
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Varadaraj A, Jenkins LM, Singh P, Chanda A, Snider J, Lee NY, Amsalem-Zafran AR, Ehrlich M, Henis YI, Mythreye K. TGF-? triggers rapid fibrillogenesis via a novel T?RII-dependent fibronectin-trafficking mechanism. Mol Biol Cell. 2017 May 01; 28(9):1195-1207.
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Iwanicki MP, Davidowitz RA, Ng MR, Besser A, Muranen T, Merritt M, Danuser G, Ince TA, Ince T, Brugge JS. Ovarian cancer spheroids use myosin-generated force to clear the mesothelium. Cancer Discov. 2011 Jul; 1(2):144-57.
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Kuwada SK, Kuang J, Li X. Integrin alpha5/beta1 expression mediates HER-2 down-regulation in colon cancer cells. J Biol Chem. 2005 May 13; 280(19):19027-35.
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Dontenwill M, Piletz JE, Chen M, Baldwin J, Pascal G, Ronde P, Dupuy L, Greney H, Takeda K, Bousquetd P. IRAS is an anti-apoptotic protein. Ann N Y Acad Sci. 2003 Dec; 1009:400-12.