GTP-Binding Protein alpha Subunits, Gi-Go

"GTP-Binding Protein alpha Subunits, Gi-Go" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A family of heterotrimeric GTP-binding protein alpha subunits that were originally identified by their ability to inhibit ADENYLYL CYCLASES. Members of this family can couple to beta and gamma G-protein subunits that activate POTASSIUM CHANNELS. The Gi-Go part of the name is also spelled Gi/Go.

Descriptor ID	D019206
MeSH Number(s)	D08.811.277.040.330.300.200.100.200 D12.644.360.360.100.200 D12.776.157.325.332.100.200 D12.776.476.375.100.200 D12.776.543.325.100.200
Concept/Terms	GTP-Binding Protein alpha Subunits, Gi-Go GTP-Binding Protein alpha Subunits, Gi-Go GTP Binding Protein alpha Subunits, Gi Go G-Protein, Gi-Go Subunits G Protein, Gi Go Subunits Gi-Go Subunits G-Protein Subunits G-Protein, Gi-Go Gi-Go G-Proteins G-Proteins, Gi-Go Gi Go G Proteins G-Protein, Gi-Go alpha Family G Protein, Gi Go alpha Family GTP-Binding Protein alpha Subunit, GoC GTP-Binding Protein alpha Subunit, GoC GTP Binding Protein alpha Subunit, GoC G Protein Subunit alphaoC GTP-Binding Protein alpha Subunit, Go1 GTP-Binding Protein alpha Subunit, Go1 GTP Binding Protein alpha Subunit, Go1 G-Protein, Go1 Subunit G Protein, Go1 Subunit Go1 Subunit G-Protein Subunit G-Protein, Go1 G(o1)alpha GTP-Binding Protein alpha Subunit, GoA GTP-Binding Protein alpha Subunit, GoA GTP Binding Protein alpha Subunit, GoA G Protein Subunit alphaoA GTP-Binding Protein alpha Subunit, Go GTP-Binding Protein alpha Subunit, Go GTP Binding Protein alpha Subunit, Go Guanine Nucleotide-Binding Protein Go Guanine Nucleotide Binding Protein Go Go Alpha Subunit Alpha Subunit, Go Subunit, Go Alpha G-Protein, Inhibitory Go G Protein, Inhibitory Go Go G-Protein, Inhibitory Inhibitory Go G-Protein G-Protein, Go Subunit G Protein, Go Subunit Go Subunit G-Protein Subunit G-Protein, Go G Protein Go Go, G Protein G(o) Protein GTP-Binding Protein alpha Subunit, Gi GTP-Binding Protein alpha Subunit, Gi GTP Binding Protein alpha Subunit, Gi Gi, Inhibitory G-Protein Gi, Inhibitory G Protein Inhibitory G-Protein Gi G-Protein, Inhibitory Gi G Protein, Inhibitory Gi Gi G-Protein, Inhibitory Inhibitory Gi G-Protein G-Protein, Gi Subunit G Protein, Gi Subunit Gi Subunit G-Protein Subunit G-Protein, Gi Gi alpha Subunit Subunit, Gi alpha alpha Subunit, Gi Ni Protein Gi-Alpha Protein Gi Alpha Protein

Below are MeSH descriptors whose meaning is more general than "GTP-Binding Protein alpha Subunits, Gi-Go".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Hydrolases [D08.811.277]
Acid Anhydride Hydrolases [D08.811.277.040]
GTP Phosphohydrolases [D08.811.277.040.330]
GTP-Binding Proteins [D08.811.277.040.330.300]
Heterotrimeric GTP-Binding Proteins [D08.811.277.040.330.300.200]
GTP-Binding Protein alpha Subunits [D08.811.277.040.330.300.200.100]
GTP-Binding Protein alpha Subunits, Gi-Go [D08.811.277.040.330.300.200.100.200]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Heterotrimeric GTP-Binding Proteins [D12.644.360.360]
GTP-Binding Protein alpha Subunits [D12.644.360.360.100]
GTP-Binding Protein alpha Subunits, Gi-Go [D12.644.360.360.100.200]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
GTP-Binding Proteins [D12.776.157.325]
Heterotrimeric GTP-Binding Proteins [D12.776.157.325.332]
GTP-Binding Protein alpha Subunits [D12.776.157.325.332.100]
GTP-Binding Protein alpha Subunits, Gi-Go [D12.776.157.325.332.100.200]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Heterotrimeric GTP-Binding Proteins [D12.776.476.375]
GTP-Binding Protein alpha Subunits [D12.776.476.375.100]
GTP-Binding Protein alpha Subunits, Gi-Go [D12.776.476.375.100.200]
Membrane Proteins [D12.776.543]
Heterotrimeric GTP-Binding Proteins [D12.776.543.325]
GTP-Binding Protein alpha Subunits [D12.776.543.325.100]
GTP-Binding Protein alpha Subunits, Gi-Go [D12.776.543.325.100.200]

Below are MeSH descriptors whose meaning is related to "GTP-Binding Protein alpha Subunits, Gi-Go".

Below are MeSH descriptors whose meaning is more specific than "GTP-Binding Protein alpha Subunits, Gi-Go".

GTP-Binding Protein alpha Subunits, Gi-Go
GTP-Binding Protein alpha Subunit, Gi2

publications

Timeline | Most Recent

This graph shows the total number of publications written about "GTP-Binding Protein alpha Subunits, Gi-Go" by people in this website by year, and whether "GTP-Binding Protein alpha Subunits, Gi-Go" was a major or minor topic of these publications.

Bar chart showing 12 publications over 11 distinct years, with a maximum of 2 publications in 2005

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	1	0	1
2005	2	0	2
2006	1	0	1
2007	0	1	1
2008	0	1	1
2009	0	1	1
2010	1	0	1
2012	0	1	1
2017	1	0	1
2018	1	0	1
2019	1	0	1

Below are the most recent publications written about "GTP-Binding Protein alpha Subunits, Gi-Go" by people in Profiles.

Li ZW, Sun B, Gong T, Guo S, Zhang J, Wang J, Sugawara A, Jiang M, Yan J, Gurary A, Zheng X, Gao B, Xiao SY, Chen W, Ma C, Farrar C, Zhu C, Chan OTM, Xin C, Winnicki A, Winnicki J, Tang M, Park R, Winnicki M, Diener K, Wang Z, Liu Q, Chu CH, Arter ZL, Yue P, Alpert L, Hui GS, Fei P, Turkson J, Yang W, Wu G, Tao A, Ramos JW, Moisyadi S, Holcombe RF, Jia W, Birnbaumer L, Zhou X, Chu WM. GNAI1 and GNAI3 Reduce Colitis-Associated Tumorigenesis in Mice by Blocking IL6 Signaling and Down-regulating Expression of GNAI2. Gastroenterology. 2019 06; 156(8):2297-2312.

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Caggia S, Chunduri H, Millena AC, Perkins JN, Venugopal SV, Vo BT, Li C, Tu Y, Khan SA. Novel role of Gia2 in cell migration: Downstream of PI3-kinase-AKT and Rac1 in prostate cancer cells. J Cell Physiol. 2018 01; 234(1):802-815.

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Zhang QH, Hao JW, Li GL, Ji XJ, Yao XD, Dong N, Yao YM. Proinflammatory switch from Gas to Gai signaling by Glucagon-like peptide-1 receptor in murine splenic monocyte following burn injury. Inflamm Res. 2018 Feb; 67(2):157-168.

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Bratton MR, Antoon JW, Duong BN, Frigo DE, Tilghman S, Collins-Burow BM, Elliott S, Tang Y, Melnik LI, Lai L, Alam J, Beckman BS, Hill SM, Rowan BG, McLachlan JA, Burow ME. Gao potentiates estrogen receptor a activity via the ERK signaling pathway. J Endocrinol. 2012 Jul; 214(1):45-54.

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Zhong M, Boseman ML, Millena AC, Khan SA. Oxytocin induces the migration of prostate cancer cells: involvement of the Gi-coupled signaling pathway. Mol Cancer Res. 2010 Aug; 8(8):1164-72.

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Chakir K, Daya SK, Aiba T, Tunin RS, Dimaano VL, Abraham TP, Jaques-Robinson KM, Jacques K, Lai EW, Pacak K, Zhu WZ, Xiao RP, Tomaselli GF, Kass DA. Mechanisms of enhanced beta-adrenergic reserve from cardiac resynchronization therapy. Circulation. 2009 Mar 10; 119(9):1231-40.

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Roychowdhury S, Rasenick MM. Submembraneous microtubule cytoskeleton: regulation of microtubule assembly by heterotrimeric Gproteins. FEBS J. 2008 Oct; 275(19):4654-63.

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McCollum L, Howlett AC, Mukhopadhyay S. Anandamide-mediated CB1/CB2 cannabinoid receptor--independent nitric oxide production in rabbit aortic endothelial cells. J Pharmacol Exp Ther. 2007 Jun; 321(3):930-7.

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Brown SL, Jala VR, Raghuwanshi SK, Nasser MW, Haribabu B, Richardson RM. Activation and regulation of platelet-activating factor receptor: role of G(i) and G(q) in receptor-mediated chemotactic, cytotoxic, and cross-regulatory signals. J Immunol. 2006 Sep 01; 177(5):3242-9.

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Tarzami ST, Calderon TM, Deguzman A, Lopez L, Kitsis RN, Berman JW. MCP-1/CCL2 protects cardiac myocytes from hypoxia-induced apoptosis by a G(alphai)-independent pathway. Biochem Biophys Res Commun. 2005 Oct 07; 335(4):1008-16.

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