GTP-Binding Protein alpha Subunit, Gi2
"GTP-Binding Protein alpha Subunit, Gi2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A PERTUSSIS TOXIN-sensitive GTP-binding protein alpha subunit. It couples with a variety of CELL SURFACE RECEPTORS, has been implicated in INTERLEUKIN-12 production, and may play a role in INFLAMMATORY BOWEL DISEASES.
| Descriptor ID |
D051960
|
| MeSH Number(s) |
D08.811.277.040.330.300.200.100.200.500 D12.644.360.360.100.200.500 D12.776.157.325.332.100.200.500 D12.776.476.375.100.200.500 D12.776.543.325.100.200.500
|
| Concept/Terms |
GTP-Binding Protein alpha Subunit, Gi2- GTP-Binding Protein alpha Subunit, Gi2
- GTP Binding Protein alpha Subunit, Gi2
- Galphai2 Protein
- Gi2-alpha Protein
- Gi2 alpha Protein
- G Protein Subunit alpha I2
- Galpha(i2) Protein
|
Below are MeSH descriptors whose meaning is more general than "GTP-Binding Protein alpha Subunit, Gi2".
- Chemicals and Drugs [D]
- Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
- Hydrolases [D08.811.277]
- Acid Anhydride Hydrolases [D08.811.277.040]
- GTP Phosphohydrolases [D08.811.277.040.330]
- GTP-Binding Proteins [D08.811.277.040.330.300]
- Heterotrimeric GTP-Binding Proteins [D08.811.277.040.330.300.200]
- GTP-Binding Protein alpha Subunits [D08.811.277.040.330.300.200.100]
- GTP-Binding Protein alpha Subunits, Gi-Go [D08.811.277.040.330.300.200.100.200]
- GTP-Binding Protein alpha Subunit, Gi2 [D08.811.277.040.330.300.200.100.200.500]
- Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
- Intracellular Signaling Peptides and Proteins [D12.644.360]
- Heterotrimeric GTP-Binding Proteins [D12.644.360.360]
- GTP-Binding Protein alpha Subunits [D12.644.360.360.100]
- GTP-Binding Protein alpha Subunits, Gi-Go [D12.644.360.360.100.200]
- GTP-Binding Protein alpha Subunit, Gi2 [D12.644.360.360.100.200.500]
- Proteins [D12.776]
- Carrier Proteins [D12.776.157]
- GTP-Binding Proteins [D12.776.157.325]
- Heterotrimeric GTP-Binding Proteins [D12.776.157.325.332]
- GTP-Binding Protein alpha Subunits [D12.776.157.325.332.100]
- GTP-Binding Protein alpha Subunits, Gi-Go [D12.776.157.325.332.100.200]
- GTP-Binding Protein alpha Subunit, Gi2 [D12.776.157.325.332.100.200.500]
- Intracellular Signaling Peptides and Proteins [D12.776.476]
- Heterotrimeric GTP-Binding Proteins [D12.776.476.375]
- GTP-Binding Protein alpha Subunits [D12.776.476.375.100]
- GTP-Binding Protein alpha Subunits, Gi-Go [D12.776.476.375.100.200]
- GTP-Binding Protein alpha Subunit, Gi2 [D12.776.476.375.100.200.500]
- Membrane Proteins [D12.776.543]
- Heterotrimeric GTP-Binding Proteins [D12.776.543.325]
- GTP-Binding Protein alpha Subunits [D12.776.543.325.100]
- GTP-Binding Protein alpha Subunits, Gi-Go [D12.776.543.325.100.200]
- GTP-Binding Protein alpha Subunit, Gi2 [D12.776.543.325.100.200.500]
Below are MeSH descriptors whose meaning is more specific than "GTP-Binding Protein alpha Subunit, Gi2".
This graph shows the total number of publications written about "GTP-Binding Protein alpha Subunit, Gi2" by people in this website by year, and whether "GTP-Binding Protein alpha Subunit, Gi2" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "GTP-Binding Protein alpha Subunit, Gi2" by people in Profiles.
-
Xu J, Kawai Y, Arinze IJ. Dual role of C/EBPa as an activator and repressor of Gai2 gene transcription. Genes Cells. 2013 Dec; 18(12):1082-94.
-
Zhong M, Clarke S, Vo BT, Khan SA. The essential role of Gia2 in prostate cancer cell migration. Mol Cancer Res. 2012 Oct; 10(10):1380-8.
-
Kawai Y, Arinze IJ. Valproic acid-induced gene expression through production of reactive oxygen species. Cancer Res. 2006 Jul 01; 66(13):6563-9.
-
Arinze IJ, Kawai Y. Transcriptional activation of the human Galphai2 gene promoter through nuclear factor-kappaB and antioxidant response elements. J Biol Chem. 2005 Mar 18; 280(11):9786-95.
-
Arinze IJ, Kawai Y. Sp family of transcription factors is involved in valproic acid-induced expression of Galphai2. J Biol Chem. 2003 May 16; 278(20):17785-91.