Genes, Tumor Suppressor

"Genes, Tumor Suppressor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Genes that inhibit expression of the tumorigenic phenotype. They are normally involved in holding cellular growth in check. When tumor suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and unregulated growth is possible.

Descriptor ID	D016147
MeSH Number(s)	G05.360.340.024.340.375.249 G05.360.340.024.340.415.400
Concept/Terms	Genes, Tumor Suppressor Genes, Tumor Suppressor Gene, Tumor Suppressor Tumor Suppressor Gene Antioncogenes Antioncogene Emerogenes Emerogene Genes, Onco-Suppressor Gene, Onco-Suppressor Genes, Onco Suppressor Onco-Suppressor Gene Onco-Suppressor Genes Cancer Suppressor Genes Cancer Suppressor Gene Gene, Cancer Suppressor Suppressor Gene, Cancer Suppressor Genes, Cancer Oncogenes, Recessive Oncogene, Recessive Recessive Oncogene Recessive Oncogenes Anti-Oncogenes Anti Oncogenes Anti-Oncogene Tumor Suppressing Genes Gene, Tumor Suppressing Genes, Tumor Suppressing Tumor Suppressing Gene Genes, Cancer Suppressor Tumor Suppressor Genes Metastasis Suppressor Genes Metastasis Suppressor Genes Gene, Metastasis Suppressor Metastasis Suppressor Gene Suppressor Gene, Metastasis Suppressor Genes, Metastasis Genes, Metastasis Suppressor Growth Suppressor Genes Growth Suppressor Genes Gene, Growth Suppressor Growth Suppressor Gene Suppressor Gene, Growth Suppressor Genes, Growth Genes, Growth Suppressor

Below are MeSH descriptors whose meaning is more general than "Genes, Tumor Suppressor".

Biological Sciences [G]
Genetic Phenomena [G05]
Genetic Structures [G05.360]
Genome [G05.360.340]
Genome Components [G05.360.340.024]
Genes [G05.360.340.024.340]
Genes, Neoplasm [G05.360.340.024.340.375]
Genes, Tumor Suppressor [G05.360.340.024.340.375.249]
Genes, Recessive [G05.360.340.024.340.415]
Genes, Tumor Suppressor [G05.360.340.024.340.415.400]

Below are MeSH descriptors whose meaning is related to "Genes, Tumor Suppressor".

Below are MeSH descriptors whose meaning is more specific than "Genes, Tumor Suppressor".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Genes, Tumor Suppressor" by people in this website by year, and whether "Genes, Tumor Suppressor" was a major or minor topic of these publications.

Bar chart showing 51 publications over 22 distinct years, with a maximum of 5 publications in 2001

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	2	1	3
1998	1	0	1
1999	1	0	1
2000	2	0	2
2001	2	3	5
2002	1	3	4
2003	0	3	3
2004	0	3	3
2005	2	2	4
2006	1	2	3
2007	0	2	2
2008	1	0	1
2009	1	0	1
2012	2	1	3
2013	2	1	3
2015	1	1	2
2016	1	2	3
2017	0	2	2
2018	1	0	1
2019	0	1	1
2020	2	0	2
2022	0	1	1

Below are the most recent publications written about "Genes, Tumor Suppressor" by people in Profiles.

Uzhachenko R, Shimamoto A, Chirwa SS, Ivanov SV, Ivanova AV, Shanker A. Mitochondrial Fus1/Tusc2 and cellular Ca2+ homeostasis: tumor suppressor, anti-inflammatory and anti-aging implications. Cancer Gene Ther. 2022 10; 29(10):1307-1320.

View in: PubMed
Dutta P, Zhang L, Zhang H, Peng Q, Montgrain PR, Wang Y, Song Y, Li J, Li WX. Unphosphorylated STAT3 in heterochromatin formation and tumor suppression in lung cancer. BMC Cancer. 2020 Feb 22; 20(1):145.

View in: PubMed
Colaprico A, Olsen C, Bailey MH, Odom GJ, Terkelsen T, Silva TC, Olsen AV, Cantini L, Zinovyev A, Barillot E, Noushmehr H, Bertoli G, Castiglioni I, Cava C, Bontempi G, Chen XS, Papaleo E. Interpreting pathways to discover cancer driver genes with Moonlight. Nat Commun. 2020 01 03; 11(1):69.

View in: PubMed
Wang Z, Katsaros D, Biglia N, Shen Y, Fu Y, Tiirikainen M, Yu H. Low expression of WWC1, a tumor suppressor gene, is associated with aggressive breast cancer and poor survival outcome. FEBS Open Bio. 2019 07; 9(7):1270-1280.

View in: PubMed
Zhang W, Flemington EK, Deng HW, Zhang K. Epigenetically Silenced Candidate Tumor Suppressor Genes in Prostate Cancer: Identified by Modeling Methylation Stratification and Applied to Progression Prediction. Cancer Epidemiol Biomarkers Prev. 2019 01; 28(1):198-207.

View in: PubMed
Vannini I, Wise PM, Challagundla KB, Plousiou M, Raffini M, Bandini E, Fanini F, Paliaga G, Crawford M, Ferracin M, Ivan C, Fabris L, Davuluri RV, Guo Z, Cortez MA, Zhang X, Chen L, Zhang S, Fernandez-Cymering C, Han L, Carloni S, Salvi S, Ling H, Murtadha M, Neviani P, Gitlitz BJ, Laird-Offringa IA, Nana-Sinkam P, Negrini M, Liang H, Amadori D, Cimmino A, Calin GA, Fabbri M. Transcribed ultraconserved region 339 promotes carcinogenesis by modulating tumor suppressor microRNAs. Nat Commun. 2017 11 27; 8(1):1801.

View in: PubMed
Zhao Y, Ling Z, Hao Y, Pang X, Han X, Califano JA, Shan L, Gu X. MiR-124 acts as a tumor suppressor by inhibiting the expression of sphingosine kinase 1 and its downstream signaling in head and neck squamous cell carcinoma. Oncotarget. 2017 Apr 11; 8(15):25005-25020.

View in: PubMed
Peres R, Furuya H, Pagano I, Shimizu Y, Hokutan K, Rosser CJ. Angiogenin contributes to bladder cancer tumorigenesis by DNMT3b-mediated MMP2 activation. Oncotarget. 2016 Jul 12; 7(28):43109-43123.

View in: PubMed
Romagnolo DF, Daniels KD, Grunwald JT, Ramos SA, Propper CR, Selmin OI. Epigenetics of breast cancer: Modifying role of environmental and bioactive food compounds. Mol Nutr Food Res. 2016 06; 60(6):1310-29.

View in: PubMed
Sheng X, Bowen N, Wang Z. GLI pathogenesis-related 1 functions as a tumor-suppressor in lung cancer. Mol Cancer. 2016 Mar 18; 15:25.

View in: PubMed

People

Explore

Similar Concepts

Top Journals