"Genes, p16" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Tumor suppressor genes located on human chromosome 9 in the region 9p21. This gene is either deleted or mutated in a wide range of malignancies. (From Segen, Current Med Talk, 1995) Two alternatively spliced gene products are encoded by p16: CYCLIN-DEPENDENT KINASE INHIBITOR P16 and TUMOR SUPPRESSOR PROTEIN P14ARF.
Descriptor ID |
D019942
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MeSH Number(s) |
G05.360.340.024.340.375.249.375 G05.360.340.024.340.415.400.375
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Concept/Terms |
Genes, p16- Genes, p16
- Genes, CDKN2
- Genes, CDKN2A
- CDKN2A Gene
- CDKN2A Genes
- Genes, MTS1
- MTS1 Gene
- Genes, p16INK4A
- p16INK4A Gene
- p16INK4A Genes
- p16 Genes
- p16 Gene
- Genes, p16INK4
- p16INK4 Gene
- p16INK4 Genes
- CDKN2 Genes
- CDKN2 Gene
- MTS1 Genes
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Below are MeSH descriptors whose meaning is more general than "Genes, p16".
Below are MeSH descriptors whose meaning is more specific than "Genes, p16".
This graph shows the total number of publications written about "Genes, p16" by people in this website by year, and whether "Genes, p16" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2001 | 0 | 1 | 1 |
2004 | 0 | 1 | 1 |
2009 | 0 | 1 | 1 |
2010 | 0 | 1 | 1 |
2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Genes, p16" by people in Profiles.
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Morris BJ, Donlon TA, He Q, Grove JS, Masaki KH, Elliott A, Willcox DC, Willcox BJ. Association analyses of insulin signaling pathway gene polymorphisms with healthy aging and longevity in Americans of Japanese ancestry. J Gerontol A Biol Sci Med Sci. 2014 Mar; 69(3):270-3.
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Sood A, Petersen H, Blanchette CM, Meek P, Picchi MA, Belinsky SA, Tesfaigzi Y. Wood smoke exposure and gene promoter methylation are associated with increased risk for COPD in smokers. Am J Respir Crit Care Med. 2010 Nov 01; 182(9):1098-104.
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Kumar K, Brim H, Giardiello F, Smoot DT, Nouraie M, Lee EL, Ashktorab H. Distinct BRAF (V600E) and KRAS mutations in high microsatellite instability sporadic colorectal cancer in African Americans. Clin Cancer Res. 2009 Feb 15; 15(4):1155-61.
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Abraham SC, Park SJ, Cruz-Correa M, Houlihan PS, Half EE, Lynch PM, Wu TT. Frequent CpG island methylation in sporadic and syndromic gastric fundic gland polyps. Am J Clin Pathol. 2004 Nov; 122(5):740-6.
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Chan J, Robinson ES, Atencio J, Wang Z, Kazianis S, Coletta LD, Nairn RS, McCarrey JR. Characterization of the CDKN2A and ARF genes in UV-induced melanocytic hyperplasias and melanomas of an opossum (Monodelphis domestica). Mol Carcinog. 2001 May; 31(1):16-26.