Oncogenes

"Oncogenes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Genes whose gain-of-function alterations lead to NEOPLASTIC CELL TRANSFORMATION. They include, for example, genes for activators or stimulators of CELL PROLIFERATION such as growth factors, growth factor receptors, protein kinases, signal transducers, nuclear phosphoproteins, and transcription factors. A prefix of "v-" before oncogene symbols indicates oncogenes captured and transmitted by RETROVIRUSES; the prefix "c-" before the gene symbol of an oncogene indicates it is the cellular homolog (PROTO-ONCOGENES) of a v-oncogene.

Descriptor ID	D009857
MeSH Number(s)	G05.360.340.024.340.375.500
Concept/Terms	Oncogenes Oncogenes Transforming Genes Transforming Gene Gene, Transforming Genes, Transforming Oncogene

Below are MeSH descriptors whose meaning is more general than "Oncogenes".

Biological Sciences [G]
Genetic Phenomena [G05]
Genetic Structures [G05.360]
Genome [G05.360.340]
Genome Components [G05.360.340.024]
Genes [G05.360.340.024.340]
Genes, Neoplasm [G05.360.340.024.340.375]
Oncogenes [G05.360.340.024.340.375.500]

Below are MeSH descriptors whose meaning is related to "Oncogenes".

Below are MeSH descriptors whose meaning is more specific than "Oncogenes".

Oncogenes
Proto-Oncogenes

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Oncogenes" by people in this website by year, and whether "Oncogenes" was a major or minor topic of these publications.

Bar chart showing 22 publications over 16 distinct years, with a maximum of 3 publications in 2004 and 2009

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	1	0	1
2002	0	1	1
2004	1	2	3
2006	0	1	1
2007	0	1	1
2008	1	0	1
2009	0	3	3
2010	1	0	1
2011	0	1	1
2012	0	1	1
2015	0	1	1
2018	1	1	2
2019	1	0	1
2020	0	2	2
2021	0	1	1
2022	0	1	1

Below are the most recent publications written about "Oncogenes" by people in Profiles.

Liu Y, Jin R, Lu H, Bian K, Wang R, Wang L, Gao R, Zhang J, Wu J, Yao X, Liu X, Liu D, Wang X, Zhang Z, Ruan K. Fragment-Based Discovery of AF9 YEATS Domain Inhibitors. Int J Mol Sci. 2022 Mar 31; 23(7).

View in: PubMed
Cagle P, Qi Q, Niture S, Kumar D. KCNQ1OT1: An Oncogenic Long Noncoding RNA. Biomolecules. 2021 10 29; 11(11).

View in: PubMed
Zhang X, Peng Y, Yuan Y, Gao Y, Hu F, Wang J, Zhu X, Feng X, Cheng Y, Wei Y, Fan X, Xie Y, Lv Y, Ashktorab H, Smoot D, Li S, Meltzer SJ, Hou G, Jin Z. Histone methyltransferase SET8 is regulated by miR-192/215 and induces oncogene-induced senescence via p53-dependent DNA damage in human gastric carcinoma cells. Cell Death Dis. 2020 10 30; 11(10):937.

View in: PubMed
Peng Y, Zhang X, Lin H, Deng S, Qin Y, Yuan Y, Feng X, Wang J, Chen W, Hu F, Yan R, Zhao Y, Cheng Y, Wei Y, Fan X, Ashktorab H, Smoot D, Li S, Meltzer SJ, Jin Z. SUFU mediates EMT and Wnt/?-catenin signaling pathway activation promoted by miRNA-324-5p in human gastric cancer. Cell Cycle. 2020 10; 19(20):2720-2733.

View in: PubMed
Dutil J, Teer JK, Golubeva V, Yoder S, Tong WL, Arroyo N, Karam R, Echenique M, Matta JL, Monteiro AN. Germline variants in cancer genes in high-risk non-BRCA patients from Puerto Rico. Sci Rep. 2019 11 28; 9(1):17769.

View in: PubMed
Niture S, Dong X, Arthur E, Chimeh U, Niture SS, Zheng W, Kumar D. Oncogenic Role of Tumor Necrosis Factor a-Induced Protein 8 (TNFAIP8). Cells. 2018 12 24; 8(1).

View in: PubMed
Zella D, Curreli S, Benedetti F, Krishnan S, Cocchi F, Latinovic OS, Denaro F, Romerio F, Djavani M, Charurat ME, Bryant JL, Tettelin H, Gallo RC. Mycoplasma promotes malignant transformation in vivo, and its DnaK, a bacterial chaperone protein, has broad oncogenic properties. Proc Natl Acad Sci U S A. 2018 12 18; 115(51):E12005-E12014.

View in: PubMed
Chaudhary K, Poirion OB, Lu L, Huang S, Ching T, Garmire LX. Multimodal Meta-Analysis of 1,494 Hepatocellular Carcinoma Samples Reveals Significant Impact of Consensus Driver Genes on Phenotypes. Clin Cancer Res. 2019 01 15; 25(2):463-472.

View in: PubMed
Flores IE, Sierra-Fonseca JA, Davalos O, Saenz LA, Castellanos MM, Zavala JK, Gosselink KL. Stress alters the expression of cancer-related genes in the prostate. BMC Cancer. 2017 Sep 05; 17(1):621.

View in: PubMed
Spencer CT, Bezbradica JS, Ramos MG, Arico CD, Conant SB, Gilchuk P, Gray JJ, Zheng M, Niu X, Hildebrand W, Link AJ, Joyce S. Viral infection causes a shift in the self peptide repertoire presented by human MHC class I molecules. Proteomics Clin Appl. 2015 Dec; 9(11-12):1035-52.

View in: PubMed

People

Explore

Similar Concepts

Top Journals