"Leukotrienes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of biologically active compounds derived from arachidonic acid by oxidative metabolism through the 5-lipoxygenase pathway. They participate in host defense reactions and pathophysiological conditions such as immediate hypersensitivity and inflammation. They have potent actions on many essential organs and systems, including the cardiovascular, pulmonary, and central nervous system as well as the gastrointestinal tract and the immune system.
| Descriptor ID |
D015289
|
| MeSH Number(s) |
D10.251.355.255.100.450 D10.251.355.310.166.887 D23.469.050.175.450
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Leukotrienes".
Below are MeSH descriptors whose meaning is more specific than "Leukotrienes".
This graph shows the total number of publications written about "Leukotrienes" by people in this website by year, and whether "Leukotrienes" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Leukotrienes" by people in Profiles.
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King AN, Fleming JK, Knapik SS, Visentin B, Wojciak JM, Huxford T. High-affinity pan-specific monoclonal antibodies that target cysteinyl leukotrienes and show efficacy in an acute model of colitis. J Lipid Res. 2017 07; 58(7):1386-1398.
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Sullivan KE. Inflammation in juvenile idiopathic arthritis. Pediatr Clin North Am. 2005 Apr; 52(2):335-57, v.
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Aliev G, Seyidov D, Neal ML, Shi J, Vigan T, Hernandez A, Folco G, Soas AH, Zimina TV, Smith MA, Perry G, Lamanna JC, Friedland RP. The effect of agonists and antagonists on the morphology of non-transformed human smooth muscle cell in vitro. J Submicrosc Cytol Pathol. 2001 Jan-Apr; 33(1-2):141-9.
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Yakubu MA, Shibata M, Leffler CW. Subarachnoid hematoma attenuates vasodilation and potentiates vasoconstriction induced by vasoactive agents in newborn pigs. Pediatr Res. 1994 Nov; 36(5):589-94.
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Gelety TJ, Chaudhuri G. Prostaglandins in the ovary and fallopian tube. Baillieres Clin Obstet Gynaecol. 1992 Dec; 6(4):707-29.