DNA Modification Methylases
"DNA Modification Methylases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that are part of the restriction-modification systems. They are responsible for producing a species-characteristic methylation pattern, on either adenine or cytosine residues, in a specific short base sequence in the host cell's own DNA. This methylated sequence will occur many times in the host-cell DNA and remain intact for the lifetime of the cell. Any DNA from another species which gains entry into a living cell and lacks the characteristic methylation pattern will be recognized by the restriction endonucleases of similar specificity and destroyed by cleavage. Most have been studied in bacterial systems, but a few have been found in eukaryotic organisms.
Descriptor ID |
D015254
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MeSH Number(s) |
D08.811.150.240 D08.811.913.555.500.350
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Concept/Terms |
DNA Modification Methylases- DNA Modification Methylases
- Methylases, DNA Modification
- Modification Methylases, DNA
- Modification Methylases
- Methylases, Modification
- DNA Modification Methyltransferases
- Methyltransferases, DNA Modification
- Modification Methyltransferases, DNA
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Below are MeSH descriptors whose meaning is more general than "DNA Modification Methylases".
Below are MeSH descriptors whose meaning is more specific than "DNA Modification Methylases".
This graph shows the total number of publications written about "DNA Modification Methylases" by people in this website by year, and whether "DNA Modification Methylases" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2009 | 0 | 1 | 1 |
2012 | 0 | 1 | 1 |
2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "DNA Modification Methylases" by people in Profiles.
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Awah CU, Winter J, Mazdoom CM, Ogunwobi OO. NSUN6, an RNA methyltransferase of 5-mC controls glioblastoma response to temozolomide (TMZ) via NELFB and RPS6KB2 interaction. Cancer Biol Ther. 2021 12 02; 22(10-12):587-597.
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Ohta K, Yamamoto M, Lin Y, Hogg N, Akiyama H, Behringer RR, Yamazaki Y. Male differentiation of germ cells induced by embryonic age-specific Sertoli cells in mice. Biol Reprod. 2012 Apr; 86(4):112.
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Akbari MR, Malekzadeh R, Shakeri R, Nasrollahzadeh D, Foumani M, Sun Y, Pourshams A, Sadjadi A, Jafari E, Sotoudeh M, Kamangar F, Boffetta P, Dawsey SM, Ghadirian P, Narod SA. Candidate gene association study of esophageal squamous cell carcinoma in a high-risk region in Iran. Cancer Res. 2009 Oct 15; 69(20):7994-8000.
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Urven LE, Weng DE, Schumaker AL, Gearhart JD, McCarrey JR. Differential gene expression in fetal mouse germ cells. Biol Reprod. 1993 Mar; 48(3):564-74.