Catechol O-Methyltransferase
"Catechol O-Methyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzyme that catalyzes the movement of a methyl group from S-adenosylmethionone to a catechol or a catecholamine.
| Descriptor ID |
D002394
|
| MeSH Number(s) |
D08.811.913.555.500.250
|
| Concept/Terms |
Catechol O-Methyltransferase- Catechol O-Methyltransferase
- O-Methyltransferase, Catechol
- Catechol-O-Methyltransferase
- Catechol O Methyltransferase
- Catechol Methyltransferase
- Methyltransferase, Catechol
|
Below are MeSH descriptors whose meaning is more general than "Catechol O-Methyltransferase".
Below are MeSH descriptors whose meaning is more specific than "Catechol O-Methyltransferase".
This graph shows the total number of publications written about "Catechol O-Methyltransferase" by people in this website by year, and whether "Catechol O-Methyltransferase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Catechol O-Methyltransferase" by people in Profiles.
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Frois T, Faria LO, Souza RP, da Silva Cunha AE, de Holanda Marinho Nogueira NG, Tavares Lim V, de Sousa Fortes L, de Miranda DM, Bertollo M, Albuquerque MR. Are COMT Val158Met (rs4680), DRD2 TaqIA (rs1800497), and BDNF Val66Met (rs6265) polymorphisms associated with executive functions performance at rest and during physical exercise? Physiol Behav. 2022 12 01; 257:113973.
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Chitrala KN, Nagarkatti P, Nagarkatti M. Computational analysis of deleterious single nucleotide polymorphisms in catechol O-Methyltransferase conferring risk to post-traumatic stress disorder. J Psychiatr Res. 2021 06; 138:207-218.
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Cunningham CL, Wu Z, Jafari A, Zhao B, Schrode K, Harkins-Perry S, Lauer A, M?ller U. The murine catecholamine methyltransferase mTOMT is essential for mechanotransduction by cochlear hair cells. Elife. 2017 05 15; 6.
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Smith ML, King J, Dent L, Mackey V, Muthian G, Griffin B, Charlton CG. Effects of acute and sub-chronic L-dopa therapy on striatal L-dopa methylation and dopamine oxidation in an MPTP mouse model of Parkinsons disease. Life Sci. 2014 Aug 06; 110(1):1-7.
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Wang P, Vadgama JV, Said JW, Magyar CE, Doan N, Heber D, Henning SM. Enhanced inhibition of prostate cancer xenograft tumor growth by combining quercetin and green tea. J Nutr Biochem. 2014 Jan; 25(1):73-80.
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Nair S, Al-Hendy A, Tamboli RA, Marks-Shulman PA, Abumrad NN. Increased COMT expression in PCOS biology. Mol Cell Endocrinol. 2012 May 15; 355(1):188-9.
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Thota C, Menon R, Wentz MJ, Fortunato SJ, Bartlett J, Drobek CO, Nair S, Al-Hendy A. A single-nucleotide polymorphism in the fetal catechol-O-methyltransferase gene is associated with spontaneous preterm birth in African Americans. Reprod Sci. 2012 Feb; 19(2):135-42.
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He Z, Sun X, Guo Z, Zhang JH. Expression and role of COMT in a rat subarachnoid hemorrhage model. Acta Neurochir Suppl. 2011; 110(Pt 1):181-7.
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Sharan C, Halder SK, Thota C, Jaleel T, Nair S, Al-Hendy A. Vitamin D inhibits proliferation of human uterine leiomyoma cells via catechol-O-methyltransferase. Fertil Steril. 2011 Jan; 95(1):247-53.
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Harirah H, Thota C, Wentz MJ, Zaman W, Al-Hendy A. Elevated expression of catechol-O-methyltransferase is associated with labor and increased prostaglandin E(2) production by human fetal membranes. Am J Obstet Gynecol. 2009 Nov; 201(5):496.e1-7.