"DNA Restriction Enzymes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that are part of the restriction-modification systems. They catalyze the endonucleolytic cleavage of DNA sequences which lack the species-specific methylation pattern in the host cell's DNA. Cleavage yields random or specific double-stranded fragments with terminal 5'-phosphates. The function of restriction enzymes is to destroy any foreign DNA that invades the host cell. Most have been studied in bacterial systems, but a few have been found in eukaryotic organisms. They are also used as tools for the systematic dissection and mapping of chromosomes, in the determination of base sequences of DNAs, and have made it possible to splice and recombine genes from one organism into the genome of another. EC 3.21.1.
| Descriptor ID |
D004262
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| MeSH Number(s) |
D08.811.150.280 D08.811.277.352.335.350.300 D08.811.277.352.355.325.300
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| Concept/Terms |
DNA Restriction Enzymes- DNA Restriction Enzymes
- Enzymes, DNA Restriction
- Restriction Enzymes, DNA
- Restriction Endonucleases
- Endonucleases, Restriction
- Restriction Endonuclease
- Endonuclease, Restriction
- DNA Restriction Enzyme
- Restriction Enzyme, DNA
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Below are MeSH descriptors whose meaning is more general than "DNA Restriction Enzymes".
Below are MeSH descriptors whose meaning is more specific than "DNA Restriction Enzymes".
This graph shows the total number of publications written about "DNA Restriction Enzymes" by people in this website by year, and whether "DNA Restriction Enzymes" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "DNA Restriction Enzymes" by people in Profiles.
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Zhou Y, Jia Y, Jarrett HW. Asymmetric polymerase chain reaction provides alternatives for preparation of (GT)5-tailed duplex DNA promoter for promoter trapping. Anal Biochem. 2012 Aug 15; 427(2):133-8.
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Yu Q, Hu N, Lu Y, Nerurkar VR, Yanagihara R. Rapid acquisition of entire DNA polymerase gene of a novel herpesvirus from green turtle fibropapilloma by a genomic walking technique. J Virol Methods. 2001 Feb; 91(2):183-95.
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Stiles JK, Shah PH, Xue L, Meade JC, Lushbaugh WB, Cleary JD, Finley RW. Molecular typing of Trichomonas vaginalis isolates by HSP70 restriction fragment length polymorphism. Am J Trop Med Hyg. 2000 Apr; 62(4):441-5.
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Valenzuela MS, Siddiqui KA. Bidirectional sequencing of supercoiled plasmid DNA. Anal Biochem. 1989 Dec; 183(2):258-62.
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Aguinaga MP, Kiper CE, Valenzuela MS. Enriched autonomously replicating sequences in a nuclear matrix-DNA complex isolated from synchronized HeLa cells. Biochem Biophys Res Commun. 1987 Apr 29; 144(2):1018-24.
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Nigro JM, Schweinfest CW, Rajkovic A, Pavlovic J, Jamal S, Dottin RP, Hart JT, Kamarck ME, Rae PM, Carty MD, et al. cDNA cloning and mapping of the human creatine kinase M gene to 19q13. Am J Hum Genet. 1987 Feb; 40(2):115-25.
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Yu H, Eckhardt LA. DNA rearrangement causes a high rate of spontaneous mutation at the immunoglobulin heavy-chain locus of a mouse myeloma cell line. Mol Cell Biol. 1986 Dec; 6(12):4228-35.
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Cavener D, Corbett G, Cox D, Whetten R. Isolation of the eclosion gene cluster and the developmental expression of the Gld gene in Drosophila melanogaster. EMBO J. 1986 Nov; 5(11):2939-48.
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Villeponteau B, Lundell M, Martinson H. Torsional stress promotes the DNAase I sensitivity of active genes. Cell. 1984 Dec; 39(3 Pt 2):469-78.
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Kwiatkowski RW, Schweinfest CW, Dottin RP. Molecular cloning and the complete nucleotide sequence of the creatine kinase-M cDNA from chicken. Nucleic Acids Res. 1984 Sep 25; 12(18):6925-34.