"Tryptophan" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An essential amino acid that is necessary for normal growth in infants and for NITROGEN balance in adults. It is a precursor of INDOLE ALKALOIDS in plants. It is a precursor of SEROTONIN (hence its use as an antidepressant and sleep aid). It can be a precursor to NIACIN, albeit inefficiently, in mammals.
| Descriptor ID |
D014364
|
| MeSH Number(s) |
D12.125.072.050.850 D12.125.142.875
|
| Concept/Terms |
Tryptophan- Tryptophan
- L-Tryptophan
- L Tryptophan
- Levotryptophan
|
Below are MeSH descriptors whose meaning is more general than "Tryptophan".
Below are MeSH descriptors whose meaning is more specific than "Tryptophan".
This graph shows the total number of publications written about "Tryptophan" by people in this website by year, and whether "Tryptophan" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1996 | 0 | 1 | 1 |
| 1997 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2001 | 1 | 1 | 2 |
| 2003 | 5 | 1 | 6 |
| 2004 | 5 | 4 | 9 |
| 2005 | 1 | 4 | 5 |
| 2007 | 2 | 2 | 4 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 2 | 1 | 3 |
| 2011 | 3 | 2 | 5 |
| 2012 | 1 | 2 | 3 |
| 2013 | 1 | 2 | 3 |
| 2014 | 3 | 2 | 5 |
| 2016 | 1 | 2 | 3 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 2 | 2 |
| 2021 | 3 | 0 | 3 |
| 2022 | 0 | 3 | 3 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Tryptophan" by people in Profiles.
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Chuang TD, Ton N, Rysling S, Quintanilla D, Boos D, Khorram O. Therapeutic effects of in?vivo administration of an inhibitor of tryptophan 2,3-dioxygenase (680c91) for the treatment of fibroids: a preclinical study. Fertil Steril. 2024 Apr; 121(4):669-678.
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Sharma S, Takkella D, Vishwakarma J, Gavvala K. Spectroscopy and dynamics of beta-lactoglobulin complexed with rifampicin. J Biomol Struct Dyn. 2024; 42(24):13460-13473.
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Wiere S, Sugai C, Espiritu MJ, Aurelio VP, Reyes CD, Yuzon N, Whittal RM, Tytgat J, Peigneur S, Bingham JP. Research into the Bioengineering of a Novel a-Conotoxin from the Milked Venom of Conus obscurus. Int J Mol Sci. 2022 Oct 11; 23(20).
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Carrico AW, Cherenack EM, Rubin LH, McIntosh R, Ghanooni D, Chavez JV, Klatt NR, Paul RH. Through the Looking-Glass: Psychoneuroimmunology and the Microbiome-Gut-Brain Axis in the Modern Antiretroviral Therapy Era. Psychosom Med. 2022 10 01; 84(8):984-994.
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Chuang TD, Quintanilla D, Boos D, Khorram O. Further characterization of tryptophan metabolism and its dysregulation in fibroids. F S Sci. 2022 11; 3(4):392-400.
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Chuang TD, Quintanilla D, Boos D, Khorram O. Tryptophan catabolism is dysregulated in leiomyomas. Fertil Steril. 2021 10; 116(4):1160-1171.
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Hsu WT, Tseng YH, Jui HY, Kuo CC, Wu KK, Lee CM. 5-Methoxytryptophan attenuates postinfarct cardiac injury by controlling oxidative stress and immune activation. J Mol Cell Cardiol. 2021 09; 158:101-114.
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Wu KK. Cytoguardin: A Tryptophan Metabolite against Cancer Growth and Metastasis. Int J Mol Sci. 2021 Apr 26; 22(9).
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Wu KK. Control of Mesenchymal Stromal Cell Senescence by Tryptophan Metabolites. Int J Mol Sci. 2021 Jan 12; 22(2).
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Zhou Y, Liu CH, Wu B, Yu X, Cheng G, Zhu K, Wang K, Zhang C, Zhao M, Zong R, Zhang L, Shi L, Alfano RR. Optical biopsy identification and grading of gliomas using label-free visible resonance Raman spectroscopy. J Biomed Opt. 2019 09; 24(9):1-12.