"5-Hydroxytryptophan" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
Descriptor ID |
D006916
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MeSH Number(s) |
D12.125.072.050.850.479
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Concept/Terms |
5-Hydroxytryptophan- 5-Hydroxytryptophan
- 5 Hydroxytryptophan
- Hydroxytryptophan
- Oxytryptophan
- Tryptophan, 5-Hydroxy-
- 5-Hydroxy- Tryptophan
- Tryptophan, 5 Hydroxy
- 5-HTP
- Oxitriptan
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Below are MeSH descriptors whose meaning is more general than "5-Hydroxytryptophan".
Below are MeSH descriptors whose meaning is more specific than "5-Hydroxytryptophan".
This graph shows the total number of publications written about "5-Hydroxytryptophan" by people in this website by year, and whether "5-Hydroxytryptophan" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1998 | 0 | 1 | 1 |
2005 | 0 | 1 | 1 |
2008 | 1 | 0 | 1 |
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Below are the most recent publications written about "5-Hydroxytryptophan" by people in Profiles.
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James NG, Byrne SL, Mason AB. Incorporation of 5-hydroxytryptophan into transferrin and its receptor allows assignment of the pH induced changes in intrinsic fluorescence when iron is released. Biochim Biophys Acta. 2009 Mar; 1794(3):532-40.
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Steele CT, Tosini G, Siopes T, Underwood H. Time keeping by the quail's eye: circadian regulation of melatonin production. Gen Comp Endocrinol. 2006 Feb; 145(3):232-6.
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Lundell MJ, Hirsh J. eagle is required for the specification of serotonin neurons and other neuroblast 7-3 progeny in the Drosophila CNS. Development. 1998 Feb; 125(3):463-72.
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Tian Y, Eaton MJ, Goudreau JL, Lookingland KJ, Moore KE. Neurochemical evidence that 5-hydroxytryptaminergic neurons tonically inhibit noradrenergic neurons terminating in the hypothalamus. Brain Res. 1993 Apr 02; 607(1-2):215-21.
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Laue TM, Senear DF, Eaton S, Ross JB. 5-hydroxytryptophan as a new intrinsic probe for investigating protein-DNA interactions by analytical ultracentrifugation. Study of the effect of DNA on self-assembly of the bacteriophage lambda cI repressor. Biochemistry. 1993 Mar 16; 32(10):2469-72.
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Ross JB, Senear DF, Waxman E, Kombo BB, Rusinova E, Huang YT, Laws WR, Hasselbacher CA. Spectral enhancement of proteins: biological incorporation and fluorescence characterization of 5-hydroxytryptophan in bacteriophage lambda cI repressor. Proc Natl Acad Sci U S A. 1992 Dec 15; 89(24):12023-7.