"Scopolamine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alkaloid from SOLANACEAE, especially DATURA and SCOPOLIA. Scopolamine and its quaternary derivatives act as antimuscarinics like ATROPINE, but may have more central nervous system effects. Among the many uses are as an anesthetic premedication, in URINARY INCONTINENCE, in MOTION SICKNESS, as an antispasmodic, and as a mydriatic and cycloplegic.
| Descriptor ID |
D012601
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| MeSH Number(s) |
D02.145.074.722.822.775 D03.132.760.180.848 D03.132.889.601.775 D03.605.084.500.722.822.775 D03.605.869.822.775
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Scopolamine".
Below are MeSH descriptors whose meaning is more specific than "Scopolamine".
This graph shows the total number of publications written about "Scopolamine" by people in this website by year, and whether "Scopolamine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Scopolamine" by people in Profiles.
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Swaminathan SK, Fisher J, Brogden NK, Kandimalla KK. Development and validation of a sensitive LC-MS/MS method for the estimation of scopolamine in human serum. J Pharm Biomed Anal. 2019 Feb 05; 164:41-46.
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Zhan X, Yin P, Heinbockel T. The basal forebrain modulates spontaneous activity of principal cells in the main olfactory bulb of anesthetized mice. Front Neural Circuits. 2013; 7:148.
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Rasmussen BA, Perry DC, O'Neil J, Manaye KF, Tizabi Y. Effects of nicotine on sensorimotor gating impairment induced by long-term treatment with neurotoxic NMDA antagonism. Neurotox Res. 2008 May-Jun; 13(3-4):151-61.
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Noailles PA, Villegas M, Ledoux M, Lucas LR, McEwen BS, Angulo JA. Acute treatment with the N-methyl-D-aspartate receptor antagonist MK-801: effect of concurrent administration of haloperidol or scopolamine on preproenkephalin mRNA levels of the striatum and nucleus accumbens of the rat brain. Neurosci Lett. 1996 Jan 05; 202(3):165-68.