Peptidoglycan

"Peptidoglycan" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A structural polymer of the bacterial cell envelope consisting of sugars and amino acids which is responsible for both shape determination and cellular integrity under osmotic stress in virtually all bacteria.

Descriptor ID	D010457
MeSH Number(s)	D09.400.420.700 D09.698.718.594 D12.644.233.594 D12.776.395.560.800 D23.050.161.616.594
Concept/Terms	Peptidoglycan Peptidoglycan Murein Pseudomurein Pseudomurein

Below are MeSH descriptors whose meaning is more general than "Peptidoglycan".

Chemicals and Drugs [D]
Carbohydrates [D09]
Glycoconjugates [D09.400]
Glycopeptides [D09.400.420]
Peptidoglycan [D09.400.420.700]
Polysaccharides [D09.698]
Polysaccharides, Bacterial [D09.698.718]
Peptidoglycan [D09.698.718.594]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Glycopeptides [D12.644.233]
Peptidoglycan [D12.644.233.594]
Proteins [D12.776]
Glycoproteins [D12.776.395]
Mucoproteins [D12.776.395.560]
Peptidoglycan [D12.776.395.560.800]
Biological Factors [D23]
Antigens [D23.050]
Antigens, Bacterial [D23.050.161]
Polysaccharides, Bacterial [D23.050.161.616]
Peptidoglycan [D23.050.161.616.594]

Below are MeSH descriptors whose meaning is related to "Peptidoglycan".

Below are MeSH descriptors whose meaning is more specific than "Peptidoglycan".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Peptidoglycan" by people in this website by year, and whether "Peptidoglycan" was a major or minor topic of these publications.

Bar chart showing 10 publications over 5 distinct years, with a maximum of 3 publications in 2004

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2004	1	2	3
2009	0	2	2
2017	2	0	2
2020	1	1	2
2025	0	1	1

Below are the most recent publications written about "Peptidoglycan" by people in Profiles.

Cheng D, Luo Z, Ning W, Heath SL, Gisslen M, Price RW, Adekunle R, Salman T, Johnson D, McKinnon JE, Ndhlovu LC, Hossain R, Hu W, Jiang W. Systemic translocation of Staphylococcus aureus promotes autoimmunity: implications in autoantibody-mediated poor immune reconstitution from antiretroviral therapy in HIV. J Virol. 2026 May 19; 100(5):e0196525.

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Broadie CO, Telchy AI, Baines AT, Dillard JP, Nicholas RA, Williams D. Coordinated Transcriptional Increases in Cell Wall Synthesis Genes in Neisseria gonorrhoeae Lacking the Lytic Transglycosylase, ltgA. Curr Microbiol. 2025 May 06; 82(6):278.

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Chan H, Taib N, Gilmore MC, Mohamed AMT, Hanna K, Luhur J, Nguyen H, Hafiz E, Cava F, Gribaldo S, Rudner D, Rodrigues CDA. Genetic Screens Identify Additional Genes Implicated in Envelope Remodeling during the Engulfment Stage of Bacillus subtilis Sporulation. mBio. 2022 10 26; 13(5):e0173222.

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Koch EJ, Bongrand C, Bennett BD, Lawhorn S, Moriano-Gutierrez S, Pende M, Vadiwala K, Dodt HU, Raible F, Goldman W, Ruby EG, McFall-Ngai M. The cytokine MIF controls daily rhythms of symbiont nutrition in an animal-bacterial association. Proc Natl Acad Sci U S A. 2020 11 03; 117(44):27578-27586.

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Garbinski LD, Rosen BP, Yoshinaga M. Organoarsenicals inhibit bacterial peptidoglycan biosynthesis by targeting the essential enzyme MurA. Chemosphere. 2020 Sep; 254:126911.

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Wang Q, Marchetti R, Prisic S, Ishii K, Arai Y, Ohta I, Inuki S, Uchiyama S, Silipo A, Molinaro A, Husson RN, Fukase K, Fujimoto Y. A Comprehensive Study of the Interaction between Peptidoglycan Fragments and the Extracellular Domain of Mycobacterium tuberculosis Ser/Thr Kinase PknB. Chembiochem. 2017 11 02; 18(21):2094-2098.

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Takeda K, Tokunaga N, Aida Y, Kajiya M, Ouhara K, Sasaki S, Mizuno N, Fujita T, Kurihara H. Brain-Derived Neurotrophic Factor Inhibits Peptidoglycan-Induced Inflammatory Cytokine Expression in Human Dental Pulp Cells. Inflammation. 2017 Feb; 40(1):240-247.

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de Buhr MF, Hedrich HJ, Westendorf AM, Obermeier F, Hofmann C, Zschemisch NH, Buer J, Bumann D, Goyert SM, Bleich A. Analysis of Cd14 as a genetic modifier of experimental inflammatory bowel disease (IBD) in mice. Inflamm Bowel Dis. 2009 Dec; 15(12):1824-36.

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Shiba H, Tsuda H, Kajiya M, Fujita T, Takeda K, Hino T, Kawaguchi H, Kurihara H. Neodymium-doped yttrium-aluminium-garnet laser irradiation abolishes the increase in interleukin-6 levels caused by peptidoglycan through the p38 mitogen-activated protein kinase pathway in human pulp cells. J Endod. 2009 Mar; 35(3):373-6.

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Janakiraman A, Goldberg MB. Recent advances on the development of bacterial poles. Trends Microbiol. 2004 Nov; 12(11):518-25.

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