Bleomycin

"Bleomycin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2. It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors.

Descriptor ID	D001761
MeSH Number(s)	D09.400.420.110 D12.644.233.110
Concept/Terms	Bleomycin Bleomycin Bleomycins BLEO-cell BLEO-cell BLEO cell BLEOcell Bleolem Bleolem Bléomycine Bellon Bléomycine Bellon Bellon, Bléomycine Bleomycin A2 Bleomycin A2 Bleomycin A(2) Bleomycin B2 Bleomycin B2 Bleomycin B(2) Bleomycin Sulfate Bleomycin Sulfate Sulfate, Bleomycin Bleomycinum Mack Bleomycinum Mack Mack, Bleomycinum Blenoxane Blenoxane Blanoxan Bleomicina Bleomicina

Below are MeSH descriptors whose meaning is more general than "Bleomycin".

Chemicals and Drugs [D]
Carbohydrates [D09]
Glycoconjugates [D09.400]
Glycopeptides [D09.400.420]
Bleomycin [D09.400.420.110]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Glycopeptides [D12.644.233]
Bleomycin [D12.644.233.110]

Below are MeSH descriptors whose meaning is related to "Bleomycin".

Below are MeSH descriptors whose meaning is more specific than "Bleomycin".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Bleomycin" by people in this website by year, and whether "Bleomycin" was a major or minor topic of these publications.

Bar chart showing 17 publications over 13 distinct years, with a maximum of 2 publications in 2000 and 2019 and 2023 and 2024

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	0	1	1
1995	0	1	1
1999	0	1	1
2000	1	1	2
2001	1	0	1
2003	1	0	1
2007	0	1	1
2013	0	1	1
2014	1	0	1
2019	0	2	2
2021	0	1	1
2023	0	2	2
2024	0	2	2

Below are the most recent publications written about "Bleomycin" by people in Profiles.

Diwan R, Bhatt HN, Dong R, Estevao IL, Varela-Ramirez A, Nurunnabi M. Cell selective BCL-2 inhibition enabled by lipid nanoparticles alleviates lung fibrosis. J Control Release. 2024 Jun; 370:421-437.

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Bhatt HN, Diwan R, Estevao IL, Dong R, Smith J, Xiao C, Agarwal SK, Nurunnabi M. Cadherin-11 targeted cell-specific liposomes enabled skin fibrosis treatment by inducing apoptosis. J Control Release. 2024 Jun; 370:110-123.

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Diwan R, Bhatt HN, Beaven E, Nurunnabi M. Emerging delivery approaches for targeted pulmonary fibrosis treatment. Adv Drug Deliv Rev. 2024 01; 204:115147.

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Ghebremedhin A, Salam AB, Adu-Addai B, Noonan S, Stratton R, Ahmed MSU, Khantwal C, Martin GR, Lin H, Andrews C, Karanam B, Rudloff U, Lopez H, Jaynes J, Yates C. A Novel CD206 Targeting Peptide Inhibits Bleomycin-Induced Pulmonary Fibrosis in Mice. Cells. 2023 04 26; 12(9).

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Nakahara Y, Hashimoto N, Sakamoto K, Enomoto A, Adams TS, Yokoi T, Omote N, Poli S, Ando A, Wakahara K, Suzuki A, Inoue M, Hara A, Mizutani Y, Imaizumi K, Kawabe T, Rosas IO, Takahashi M, Kaminski N, Hasegawa Y. Fibroblasts positive for meflin have anti-fibrotic properties in pulmonary fibrosis. Eur Respir J. 2021 12; 58(6).

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Piccolo V, Corneli P, Zalaudek I, Argenziano G, Conforti C, Alfano R, Russo T. Mees' lines because of chemotherapy for Hodgkin's lymphoma. Int J Dermatol. 2020 Feb; 59(2):e38.

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Urushiyama H, Terasaki Y, Nagasaka S, Kokuho N, Endo Y, Terasaki M, Kunugi S, Makita K, Isago H, Hosoki K, Souma K, Ishii T, Matsuzaki H, Hiraishi Y, Mikami Y, Noguchi S, Tamiya H, Mitani A, Yamauchi Y, Shimizu A, Nagase T. Naftopidil reduced the proliferation of lung fibroblasts and bleomycin-induced lung fibrosis in mice. J Cell Mol Med. 2019 05; 23(5):3563-3571.

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Lee WJ, Lee SM, Won CH, Chang SE, Lee MW, Choi JH, Moon KC. Efficacy of intralesional bleomycin for the treatment of plantar hard corns. Int J Dermatol. 2014 Dec; 53(12):e572-7.

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Le Saux CJ, Davy P, Brampton C, Ahuja SS, Fauce S, Shivshankar P, Nguyen H, Ramaseshan M, Tressler R, Pirot Z, Harley CB, Allsopp R. A novel telomerase activator suppresses lung damage in a murine model of idiopathic pulmonary fibrosis. PLoS One. 2013; 8(3):e58423.

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Mandal S, Mandal AK. Malignant fibrous histiocytoma following radiation therapy and chemotherapy for Hodgkin's lymphoma. Int J Clin Oncol. 2007 Feb; 12(1):52-5.

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