Lipopolysaccharides

"Lipopolysaccharides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Lipid-containing polysaccharides which are endotoxins and important group-specific antigens. They are often derived from the cell wall of gram-negative bacteria and induce immunoglobulin secretion. The lipopolysaccharide molecule consists of three parts: LIPID A, core polysaccharide, and O-specific chains (O ANTIGENS). When derived from Escherichia coli, lipopolysaccharides serve as polyclonal B-cell mitogens commonly used in laboratory immunology. (From Dorland, 28th ed)

Descriptor ID	D008070
MeSH Number(s)	D09.400.500 D09.698.718.450 D10.494 D23.050.161.616.525 D23.946.123.329.500
Concept/Terms	Lipopolysaccharides Lipopolysaccharides Lipoglycans

Below are MeSH descriptors whose meaning is more general than "Lipopolysaccharides".

Chemicals and Drugs [D]
Carbohydrates [D09]
Glycoconjugates [D09.400]
Lipopolysaccharides [D09.400.500]
Polysaccharides [D09.698]
Polysaccharides, Bacterial [D09.698.718]
Lipopolysaccharides [D09.698.718.450]
Lipids [D10]
Lipopolysaccharides [D10.494]
Biological Factors [D23]
Antigens [D23.050]
Antigens, Bacterial [D23.050.161]
Polysaccharides, Bacterial [D23.050.161.616]
Lipopolysaccharides [D23.050.161.616.525]
Toxins, Biological [D23.946]
Bacterial Toxins [D23.946.123]
Endotoxins [D23.946.123.329]
Lipopolysaccharides [D23.946.123.329.500]

Below are MeSH descriptors whose meaning is related to "Lipopolysaccharides".

Below are MeSH descriptors whose meaning is more specific than "Lipopolysaccharides".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Lipopolysaccharides" by people in this website by year, and whether "Lipopolysaccharides" was a major or minor topic of these publications.

Bar chart showing 171 publications over 28 distinct years, with a maximum of 15 publications in 2004

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	2	2
1999	0	1	1
2000	0	3	3
2001	4	1	5
2002	4	7	11
2003	2	5	7
2004	4	11	15
2005	3	2	5
2006	3	3	6
2007	6	3	9
2008	2	3	5
2009	2	6	8
2010	2	5	7
2011	6	2	8
2012	1	4	5
2013	2	6	8
2014	2	2	4
2015	1	5	6
2016	1	10	11
2017	1	4	5
2018	4	4	8
2019	2	3	5
2020	2	4	6
2021	2	2	4
2022	0	3	3
2023	0	6	6
2024	2	3	5
2025	0	3	3

Below are the most recent publications written about "Lipopolysaccharides" by people in Profiles.

Colomer-Winter C, Nair ZJ, Chua JYJ, Jabli S, Roch M, Cazenave-Gassiot A, Sierra R, Andrey DO, Chng SS, Kline KA. A two-component system signaling hub controls enterococcal membrane remodeling in response to daptomycin. Proc Natl Acad Sci U S A. 2026 Apr 28; 123(17):e2532437123.

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Shipman JG, Mundy K, Onyenwoke RU, Sivaraman V. Vaping induces a marked pro-inflammatory state within the lung, which is at least partially due to its immunomodulatory effects. Front Immunol. 2026; 17:1759361.

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Zalucha EM, Hutch CR, Bethea M, Cook TM, Unadkat A, Wells KL, Kim KS, Maerz B, Lehrke M, Singer K, Sandoval DA. The Role of Pancreatic Preproglucagon in Regulating Local Inflammation in Mice. Cells. 2026 Mar 06; 15(5).

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Armina-Rodriguez A, Dorta-Estremera SM, Mendez LB, Espino AM. Protection of mice against septic shock induced by lethal intraperitoneal dose of LPS by a recombinant Fasciola hepatica fatty acid binding protein. Microbiol Spectr. 2026 Apr 07; 14(4):e0275625.

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Armina-Rodriguez A, Vald?s Fernandez BN, Ocasio-Malav? C, Cantres Rosario YM, Carrasquillo Carri?n K, Mel?ndez LM, Roche Lima A, Tosado Rodriguez EL, Espino AM. Quantitative Proteomics Reveals Fh15 as an Antagonist of TLR4 Downregulating the Activation of NF-?B, Inducible Nitric Oxide, Phagosome Signaling Pathways, and Oxidative Stress of LPS-Stimulated Macrophages. Int J Mol Sci. 2025 Jul 18; 26(14).

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Lee HJ, Lee NK, Kim J, Kim J, Seo D, Shin HE, Kim J, Ahn JH, Kim SN, Kim HS, Park J, Park W, Hong KS, Park CG, Lee W. Sequential nanoparticle therapy targeting neutrophil hyperactivation to prevent neutrophil-induced pulmonary fibrosis. J Nanobiotechnology. 2025 May 26; 23(1):381.

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Rorex C, Cardona SM, Church KA, Rodriguez D, Vanegas D, Saldivar RA, El-Sheikh A, Wang Y, Gyoneva S, Cotleur AC, Cardona AE. CX3CR1-Fractalkine Dysregulation Affects Retinal GFAP Expression, Inflammatory Gene Induction, and LPS Response in a Mouse Model of Hypoxic Retinopathy. Int J Mol Sci. 2025 Jan 28; 26(3).

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Warner S, Teague HL, Ramos-Benitez MJ, Panicker S, Allen K, Gairhe S, Moyer T, Parachalil Gopalan B, Douagi I, Shet A, Kanthi Y, Suffredini AF, Chertow DS, Strich JR. R406 reduces lipopolysaccharide-induced neutrophil activation. Cell Immunol. 2024 Sep-Oct; 403-404:104860.

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Ma C, Hoffmann FW, Shay AE, Koo I, Green KA, Green WR, Hoffmann PR. Upregulated selenoprotein I during lipopolysaccharide-induced B cell activation promotes lipidomic changes and is required for effective differentiation into IgM-secreting plasma B cells. J Leukoc Biol. 2024 06 28; 116(1):6-17.

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Sampath C, Chukkapalli SS, Raju AV, Alluri LSC, Srisai D, Gangula PR. Cinnamaldehyde Protects against P. gingivalis Induced Intestinal Epithelial Barrier Dysfunction in IEC-6 Cells via the PI3K/Akt-Mediated NO/Nrf2 Signaling Pathway. Int J Mol Sci. 2024 Apr 26; 25(9).

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