"Metyrapone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
Descriptor ID |
D008797
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MeSH Number(s) |
D03.383.725.463
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Metyrapone".
Below are MeSH descriptors whose meaning is more specific than "Metyrapone".
This graph shows the total number of publications written about "Metyrapone" by people in this website by year, and whether "Metyrapone" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2013 | 1 | 0 | 1 |
2014 | 2 | 0 | 2 |
2016 | 1 | 0 | 1 |
2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Metyrapone" by people in Profiles.
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Chuang TD, Sakurai R, Gong M, Khorram O, Rehan VK. Role of miR-29 in mediating offspring lung phenotype in a rodent model of intrauterine growth restriction. Am J Physiol Regul Integr Comp Physiol. 2018 11 01; 315(5):R1017-R1026.
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Geronimo I, Denning CA, Rogers WE, Othman T, Huxford T, Heidary DK, Glazer EC, Payne CM. Effect of Mutation and Substrate Binding on the Stability of Cytochrome P450BM3 Variants. Biochemistry. 2016 06 28; 55(25):3594-606.
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Paek DS, Sakurai R, Saraswat A, Li Y, Khorram O, Torday JS, Rehan VK. Metyrapone alleviates deleterious effects of maternal food restriction on lung development and growth of rat offspring. Reprod Sci. 2015 Feb; 22(2):207-22.
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Durrant LM, Khorram O, Buchholz JN, Pearce WJ. Maternal food restriction modulates cerebrovascular structure and contractility in adult rat offspring: effects of metyrapone. Am J Physiol Regul Integr Comp Physiol. 2014 Mar 15; 306(6):R401-10.
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Rehan VK, Li Y, Corral J, Saraswat A, Husain S, Dhar A, Sakurai R, Khorram O, Torday JS. Metyrapone blocks maternal food restriction-induced changes in female rat offspring lung development. Reprod Sci. 2014 Apr; 21(4):517-25.