2-Pyridinylmethylsulfinylbenzimidazoles
"2-Pyridinylmethylsulfinylbenzimidazoles" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds that contain benzimidazole joined to a 2-methylpyridine via a sulfoxide linkage. Several of the compounds in this class are ANTI-ULCER AGENTS that act by inhibiting the POTASSIUM HYDROGEN ATPASE found in the PROTON PUMP of GASTRIC PARIETAL CELLS.
Descriptor ID |
D053799
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MeSH Number(s) |
D02.886.640.074 D03.383.725.024 D03.633.100.103.034
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Concept/Terms |
2-Pyridinylmethylsulfinylbenzimidazoles- 2-Pyridinylmethylsulfinylbenzimidazoles
- 2 Pyridinylmethylsulfinylbenzimidazoles
- Benzimidazole Methylpyridine Sulfoxides
- Methylpyridine Sulfoxides, Benzimidazole
- Sulfoxides, Benzimidazole Methylpyridine
Timoprazole Derivatives- Timoprazole Derivatives
- Timoprazoles
- 2-Methylpyridine 2-Benzimidazole Sulfoxides
- 2 Methylpyridine 2 Benzimidazole Sulfoxides
- 2-Benzimidazole Sulfoxides, 2-Methylpyridine
- Sulfoxides, 2-Methylpyridine 2-Benzimidazole
- 2-Pyridinylmethylsulfinyl-2-Benzimidazoles
- 2 Pyridinylmethylsulfinyl 2 Benzimidazoles
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Below are MeSH descriptors whose meaning is more general than "2-Pyridinylmethylsulfinylbenzimidazoles".
Below are MeSH descriptors whose meaning is more specific than "2-Pyridinylmethylsulfinylbenzimidazoles".
This graph shows the total number of publications written about "2-Pyridinylmethylsulfinylbenzimidazoles" by people in this website by year, and whether "2-Pyridinylmethylsulfinylbenzimidazoles" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2003 | 0 | 2 | 2 |
2006 | 1 | 0 | 1 |
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Below are the most recent publications written about "2-Pyridinylmethylsulfinylbenzimidazoles" by people in Profiles.
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El-Sherif ZA, Mohamed AO, El-Bardicy MG, El-Tarras MF. Reversed-phase high performance liquid chromatographic method for the determination of lansoprazole, omeprazole and pantoprazole sodium sesquihydrate in presence of their Acid-induced degradation products. Chem Pharm Bull (Tokyo). 2006 Jun; 54(6):814-8.
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Biswas K, Bandyopadhyay U, Chattopadhyay I, Varadaraj A, Ali E, Banerjee RK. A novel antioxidant and antiapoptotic role of omeprazole to block gastric ulcer through scavenging of hydroxyl radical. J Biol Chem. 2003 Mar 28; 278(13):10993-1001.
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Adachi K, Komazawa Y, Fujishiro H, Mihara T, Ono M, Yuki M, Kawamura A, Karim Rumi MA, Amano Y, Kinoshita Y. Nocturnal gastric acid breakthrough during the administration of rabeprazole and ranitidine in Helicobacter pylori-negative subjects: effects of different regimens. J Gastroenterol. 2003; 38(9):830-5.