"Ketocholesterols" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cholesterol substituted in any position by a keto moiety. The 7-keto isomer inhibits cholesterol uptake in the coronary arteries and aorta by blocking 3-hydroxy-3-methylglutaryl-CoA reductase activity.
Descriptor ID |
D007653
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MeSH Number(s) |
D04.210.500.247.222.265.450 D04.210.500.247.222.284.800.750 D04.210.500.247.808.197.800.750 D10.570.938.208.825.750
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Ketocholesterols".
Below are MeSH descriptors whose meaning is more specific than "Ketocholesterols".
This graph shows the total number of publications written about "Ketocholesterols" by people in this website by year, and whether "Ketocholesterols" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2006 | 1 | 0 | 1 |
2007 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ketocholesterols" by people in Profiles.
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Guo Z, Ran Q, Roberts LJ, Zhou L, Richardson A, Sharan C, Wu D, Yang H. Suppression of atherogenesis by overexpression of glutathione peroxidase-4 in apolipoprotein E-deficient mice. Free Radic Biol Med. 2008 Feb 01; 44(3):343-52.
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Zhou L, Shi M, Guo Z, Brisbon W, Hoover R, Yang H. Different cytotoxic injuries induced by lysophosphatidylcholine and 7-ketocholesterol in mouse endothelial cells. Endothelium. 2006 May-Jun; 13(3):213-26.