Hydroxycholesterols

"Hydroxycholesterols" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Cholesterol which is substituted by a hydroxy group in any position.

Descriptor ID	D006888
MeSH Number(s)	D04.210.500.247.222.284.800.500 D04.210.500.247.808.197.800.500 D10.570.938.208.825.500
Concept/Terms	Hydroxycholesterols Hydroxycholesterols

Below are MeSH descriptors whose meaning is more general than "Hydroxycholesterols".

Chemicals and Drugs [D]
Polycyclic Compounds [D04]
Fused-Ring Compounds [D04.210]
Steroids [D04.210.500]
Cholestanes [D04.210.500.247]
Cholestenes [D04.210.500.247.222]
Cholesterol [D04.210.500.247.222.284]
Oxysterols [D04.210.500.247.222.284.800]
Hydroxycholesterols [D04.210.500.247.222.284.800.500]
Sterols [D04.210.500.247.808]
Cholesterol [D04.210.500.247.808.197]
Oxysterols [D04.210.500.247.808.197.800]
Hydroxycholesterols [D04.210.500.247.808.197.800.500]
Lipids [D10]
Membrane Lipids [D10.570]
Sterols [D10.570.938]
Cholesterol [D10.570.938.208]
Oxysterols [D10.570.938.208.825]
Hydroxycholesterols [D10.570.938.208.825.500]

Below are MeSH descriptors whose meaning is related to "Hydroxycholesterols".

Below are MeSH descriptors whose meaning is more specific than "Hydroxycholesterols".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Hydroxycholesterols" by people in this website by year, and whether "Hydroxycholesterols" was a major or minor topic of these publications.

Bar chart showing 11 publications over 10 distinct years, with a maximum of 2 publications in 1997

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	2	0	2
1999	1	0	1
2002	0	1	1
2006	0	1	1
2009	0	1	1
2010	0	1	1
2011	0	1	1
2023	0	1	1
2024	1	0	1
2025	1	0	1

Below are the most recent publications written about "Hydroxycholesterols" by people in Profiles.

Li Y, Streicher SA, Franke AA, Tome AN, White KK, Shvetsov Y, Lim U, Setiawan VW, DeRouen MC, Hernandez BY, Wu AH, Wilkens LR, Le Marchand L, Loo LWM, Cheng I. Association of Adiposity Phenotypes With 27-Hydroxycholesterol and Sex Hormones: The Multiethnic Cohort Study. J Clin Endocrinol Metab. 2025 Apr 22; 110(5):e1488-e1498.

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Sun H, Yang T, Simon RP, Xiong ZG, Leng T. Role of Cholesterol Metabolic Enzyme CYP46A1 and Its Metabolite 24S-Hydroxycholesterol in Ischemic Stroke. Stroke. 2024 10; 55(10):2492-2501.

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DeRouen MC, Yang J, Li Y, Franke AA, Tome AN, White KK, Hernandez BY, Shvetsov Y, Setiawan V, Wu AH, Wilkens LR, Le Marchand L, Loo LWM, Cheng I. Circulating 27-hydroxycholesterol, lipids, and steroid hormones in breast cancer risk: a nested case-control study of the Multiethnic Cohort Study. Breast Cancer Res. 2023 08 14; 25(1):95.

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Dambal S, Alfaqih M, Sanders S, Maravilla E, Ramirez-Torres A, Galvan GC, Reis-Sobreiro M, Rotinen M, Driver LM, Behrove MS, Talisman TJ, Yoon J, You S, Turkson J, Chi JT, Freeman MR, Macias E, Freedland SJ. 27-Hydroxycholesterol Impairs Plasma Membrane Lipid Raft Signaling as Evidenced by Inhibition of IL6-JAK-STAT3 Signaling in Prostate Cancer Cells. Mol Cancer Res. 2020 05; 18(5):671-684.

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Chang LL, Wun WS, Wang PS. Effects of nonylphenol on aldosterone release from rat zona glomerulosa cells. Chem Biol Interact. 2012 Jan 05; 195(1):11-7.

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Chang LL, Alfred Wun WS, Wang PS. Effects and mechanisms of nonylphenol on corticosterone release in rat zona fasciculata-reticularis cells. Toxicol Sci. 2010 Dec; 118(2):411-9.

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Yu PL, Chao HL, Wang SW, Wang PS. Effects of evodiamine and rutaecarpine on the secretion of corticosterone by zona fasciculata-reticularis cells in male rats. J Cell Biochem. 2009 Oct 01; 108(2):469-75.

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Chang LL, Wun AW, Hung CT, Hsia SM, Chiang W, Wang PS. Effects of crude adlay hull acetone extract on corticosterone release from rat zona fasciculata-reticularis cells. Naunyn Schmiedebergs Arch Pharmacol. 2006 Nov; 374(2):141-52.

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Yee WL, Wang Q, Agdinaoay T, Dang K, Chang H, Grandinetti A, Franke AA, Theriault A. Green tea catechins decrease apolipoprotein B-100 secretion from HepG2 cells. Mol Cell Biochem. 2002 Jan; 229(1-2):85-92.

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Ayala-Torres S, Zhou F, Thompson EB. Apoptosis induced by oxysterol in CEM cells is associated with negative regulation of c-myc. Exp Cell Res. 1999 Jan 10; 246(1):193-202.

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