The most abundant protein component of HIGH DENSITY LIPOPROTEINS or HDL. This protein serves as an acceptor for CHOLESTEROL released from cells thus promoting efflux of cholesterol to HDL then to the LIVER for excretion from the body (reverse cholesterol transport). It also acts as a cofactor for LECITHIN CHOLESTEROL ACYLTRANSFERASE that forms CHOLESTEROL ESTERS on the HDL particles. Mutations of this gene APOA1 cause HDL deficiency, such as in FAMILIAL ALPHA LIPOPROTEIN DEFICIENCY DISEASE and in some patients with TANGIER DISEASE.

Descriptor ID	D016632
MeSH Number(s)	D10.532.091.200.100 D12.776.070.400.200.100 D12.776.521.120.200.100
Concept/Terms	Apolipoprotein A-I Apolipoprotein A-I Apolipoprotein A I Apo A-I Apo A1 Apolipoprotein AI ApoA-1 ApoA-I Apolipoprotein A-1 Apolipoprotein A 1 Apolipoprotein A1 Apo A-1 Apo AI Pro-Apolipoprotein A-I Pro-Apolipoprotein A-I Pro Apolipoprotein A I Pro-Apo A-I Pro Apo A I Proapolipoprotein AI Apolipoprotein AI Propeptide Apolipoprotein A-I Isoproteins Apolipoprotein A-I Isoproteins Apolipoprotein A I Isoproteins Apo A-I Isoproteins Apo A I Isoproteins Apolipoprotein A-I Isoprotein-2 Apolipoprotein A-I Isoprotein-2 Apolipoprotein A I Isoprotein 2 Apolipoprotein A-I Isoprotein-4 Apolipoprotein A-I Isoprotein-4 Apolipoprotein A I Isoprotein 4

Below are MeSH descriptors whose meaning is more general than "Apolipoprotein A-I".

Below are MeSH descriptors whose meaning is related to "Apolipoprotein A-I".

Below are MeSH descriptors whose meaning is more specific than "Apolipoprotein A-I".