"Genes, Lethal" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genes whose loss of function or gain of function MUTATION leads to the death of the carrier prior to maturity. They may be essential genes (GENES, ESSENTIAL) required for viability, or genes which cause a block of function of an essential gene at a time when the essential gene function is required for viability.
| Descriptor ID |
D005804
|
| MeSH Number(s) |
G05.360.340.024.340.350
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Genes, Lethal".
Below are MeSH descriptors whose meaning is more specific than "Genes, Lethal".
This graph shows the total number of publications written about "Genes, Lethal" by people in this website by year, and whether "Genes, Lethal" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
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Below are the most recent publications written about "Genes, Lethal" by people in Profiles.
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Duttaroy A, Paul A, Kundu M, Belton A. A Sod2 null mutation confers severely reduced adult life span in Drosophila. Genetics. 2003 Dec; 165(4):2295-9.
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Qiu P, Pan PC, Govind S. A role for the Drosophila Toll/Cactus pathway in larval hematopoiesis. Development. 1998 May; 125(10):1909-20.
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Govind S. Rel signalling pathway and the melanotic tumour phenotype of Drosophila. Biochem Soc Trans. 1996 Feb; 24(1):39-44.