"Genes, Immediate-Early" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genes that show rapid and transient expression in the absence of de novo protein synthesis. The term was originally used exclusively for viral genes where immediate-early referred to transcription immediately following virus integration into the host cell. It is also used to describe cellular genes which are expressed immediately after resting cells are stimulated by extracellular signals such as growth factors and neurotransmitters.
| Descriptor ID |
D017781
|
| MeSH Number(s) |
G05.360.340.024.340.330 G05.360.340.024.340.364.875.345 G05.360.340.358.024.875.345 G05.360.340.358.840.500.345
|
| Concept/Terms |
Genes, Immediate-Early- Genes, Immediate-Early
- Genes, Immediate Early
- Immediate-Early Genes
- Gene, Immediate-Early
- Immediate Early Genes
- Immediate-Early Gene
|
Below are MeSH descriptors whose meaning is more general than "Genes, Immediate-Early".
- Biological Sciences [G]
- Genetic Phenomena [G05]
- Genetic Structures [G05.360]
- Genome [G05.360.340]
- Genome Components [G05.360.340.024]
- Genes [G05.360.340.024.340]
- Genes, Immediate-Early [G05.360.340.024.340.330]
- Genes, Microbial [G05.360.340.024.340.364]
- Genes, Viral [G05.360.340.024.340.364.875]
- Genes, Immediate-Early [G05.360.340.024.340.364.875.345]
- Genome, Microbial [G05.360.340.358]
- Genes, Microbial [G05.360.340.358.024]
- Genes, Viral [G05.360.340.358.024.875]
- Genes, Immediate-Early [G05.360.340.358.024.875.345]
- Genome, Viral [G05.360.340.358.840]
- Genes, Viral [G05.360.340.358.840.500]
- Genes, Immediate-Early [G05.360.340.358.840.500.345]
Below are MeSH descriptors whose meaning is more specific than "Genes, Immediate-Early".
This graph shows the total number of publications written about "Genes, Immediate-Early" by people in this website by year, and whether "Genes, Immediate-Early" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 1 | 2 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Genes, Immediate-Early" by people in Profiles.
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Santarelli AJ, Khan AM, Poulos AM. Contextual fear retrieval-induced Fos expression across early development in the rat: An analysis using established nervous system nomenclature ontology. Neurobiol Learn Mem. 2018 11; 155:42-49.
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Adamik J, Wang KZ, Unlu S, Su AJ, Tannahill GM, Galson DL, O'Neill LA, Auron PE. Distinct mechanisms for induction and tolerance regulate the immediate early genes encoding interleukin 1? and tumor necrosis factor a. PLoS One. 2013; 8(8):e70622.
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Cosme RS, Yamamura Y, Tang Q. Roles of polypyrimidine tract binding proteins in major immediate-early gene expression and viral replication of human cytomegalovirus. J Virol. 2009 Apr; 83(7):2839-50.
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Sun WL, Zhou L, Hazim R, Quinones-Jenab V, Jenab S. Effects of dopamine and NMDA receptors on cocaine-induced Fos expression in the striatum of Fischer rats. Brain Res. 2008 Dec 03; 1243:1-9.
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Michaels MG, Alcendor DJ, St George K, Rinaldo CR, Ehrlich GD, Becich MJ, Hayward GS. Distinguishing baboon cytomegalovirus from human cytomegalovirus: importance for xenotransplantation. J Infect Dis. 1997 Dec; 176(6):1476-83.
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Jenab S, Morris PL. Transcriptional regulation of Sertoli cell immediate early genes by interleukin-6 and interferon-gamma is mediated through phosphorylation of STAT-3 and STAT-1 proteins. Endocrinology. 1997 Jul; 138(7):2740-6.
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Polston EK, Erskine MS. Patterns of induction of the immediate-early genes c-fos and egr-1 in the female rat brain following differential amounts of mating stimulation. Neuroendocrinology. 1995 Oct; 62(4):370-84.