Carbazoles

"Carbazoles" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Benzo-indoles similar to CARBOLINES which are pyrido-indoles. In plants, carbazoles are derived from indole and form some of the INDOLE ALKALOIDS.

Descriptor ID	D002227
MeSH Number(s)	D03.633.100.473.144 D03.633.300.148
Concept/Terms	Carbazoles Carbazoles

Below are MeSH descriptors whose meaning is more general than "Carbazoles".

Chemicals and Drugs [D]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, Fused-Ring [D03.633]
Heterocyclic Compounds, 2-Ring [D03.633.100]
Indoles [D03.633.100.473]
Carbazoles [D03.633.100.473.144]
Heterocyclic Compounds, 3-Ring [D03.633.300]
Carbazoles [D03.633.300.148]

Below are MeSH descriptors whose meaning is more specific than "Carbazoles".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Carbazoles" by people in this website by year, and whether "Carbazoles" was a major or minor topic of these publications.

Bar chart showing 25 publications over 18 distinct years, with a maximum of 3 publications in 2006

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	2	0	2
2003	1	0	1
2004	1	1	2
2006	2	1	3
2007	1	0	1
2008	1	0	1
2009	0	1	1
2010	0	1	1
2012	1	1	2
2013	2	0	2
2014	1	0	1
2015	1	0	1
2016	1	0	1
2017	0	1	1
2018	1	1	2
2019	1	0	1
2020	0	1	1
2021	0	1	1

Below are the most recent publications written about "Carbazoles" by people in Profiles.

Borrero-Garc?a LD, Del Mar Maldonado M, Medina-Vel?zquez J, Troche-Torres AL, Velazquez L, Grafals-Ruiz N, Dharmawardhane S. Rac inhibition as a novel therapeutic strategy for EGFR/HER2 targeted therapy resistant breast cancer. BMC Cancer. 2021 Jun 01; 21(1):652.

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Zhang L, Leng TD, Yang T, Li J, Xiong ZG. Protein Kinase C Regulates ASIC1a Protein Expression and Channel Function via NF-kB Signaling Pathway. Mol Neurobiol. 2020 Nov; 57(11):4754-4766.

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Butler-Fern?ndez KM, Ramos Z, Francis-Malav? AM, Bloom J, Dharmawardhane S, Hern?ndez E. Synthesis, Anti-Cancer and Anti-Migratory Evaluation of 3,6-Dibromocarbazole and 5-Bromoindole Derivatives. Molecules. 2019 Jul 24; 24(15).

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Chitrala KN, Yang X, Nagarkatti P, Nagarkatti M. Comparative analysis of interactions between aryl hydrocarbon receptor ligand binding domain with its ligands: a computational study. BMC Struct Biol. 2018 12 06; 18(1):15.

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Vlaar CP, Castillo-Pichardo L, Medina JI, Marrero-Serra CM, V?lez E, Ramos Z, Hern?ndez E. Design, synthesis and biological evaluation of new carbazole derivatives as anti-cancer and anti-migratory agents. Bioorg Med Chem. 2018 02 15; 26(4):884-890.

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Humphries-Bickley T, Castillo-Pichardo L, Hernandez-O'Farrill E, Borrero-Garcia LD, Forestier-Roman I, Gerena Y, Blanco M, Rivera-Robles MJ, Rodriguez-Medina JR, Cubano LA, Vlaar CP, Dharmawardhane S. Characterization of a Dual Rac/Cdc42 Inhibitor MBQ-167 in Metastatic Cancer. Mol Cancer Ther. 2017 05; 16(5):805-818.

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Zhuang X, Ma X, Xue X, Jiang Q, Song L, Dai L, Zhang C, Jin S, Yang K, Ding B, Wang PC, Liang XJ. A Photosensitizer-Loaded DNA Origami Nanosystem for Photodynamic Therapy. ACS Nano. 2016 Mar 22; 10(3):3486-95.

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Humphries-Bickley T, Castillo-Pichardo L, Corujo-Carro F, Duconge J, Hernandez-O'Farrill E, Vlaar C, Rodriguez-Orengo JF, Cubano L, Dharmawardhane S. Pharmacokinetics of Rac inhibitor EHop-016 in mice by ultra-performance liquid chromatography tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Feb 15; 981-982:19-26.

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Chang L, Podoll JD, Wang W, Walls S, O'Rourke CP, Wang X. Structure-activity relationship studies of the tricyclic indoline resistance-modifying agent. J Med Chem. 2014 May 08; 57(9):3803-17.

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Martin H, Mali RS, Ma P, Chatterjee A, Ramdas B, Sims E, Munugalavadla V, Ghosh J, Mattingly RR, Visconte V, Tiu RV, Vlaar CP, Dharmawardhane S, Kapur R. Pak and Rac GTPases promote oncogenic KIT-induced neoplasms. J Clin Invest. 2013 Oct; 123(10):4449-63.

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