Structure-activity relationships of 6-(aminomethylphenoxy)-benzoxaborole derivatives as anti-inflammatory agent.

Akama T, Virtucio C, Dong C, Kimura R, Zhang YK, Nieman JA, Sharma R, Lu X, Sales M, Singh R, Wu A, Fan XQ, Liu L, Plattner JJ, Jarnagin K, Freund YR. Structure-activity relationships of 6-(aminomethylphenoxy)-benzoxaborole derivatives as anti-inflammatory agent. Bioorg Med Chem Lett. 2013 Mar 15; 23(6):1680-3.

View in: PubMed

subject areas

Animals
Anti-Inflammatory Agents
Benzoxazoles
Boron Compounds
Half-Life
Humans
Interleukin-1beta
Interleukin-6
Kinetics
Leukocytes, Mononuclear
Lipopolysaccharides
Mice
Protein Binding
Structure-Activity Relationship
Tumor Necrosis Factor-alpha

authors with profiles

Rajesh Singh

RCMI CC is supported by the National Institute on Minority Health and Health Disparities, National Institutes of Health (NIH), through Grant Number U24MD015970. The contents of this site are solely the responsibility of the authors and do not necessarily represent the official views of the NIH

For technical support please contact support