T-cell activation and receptor downmodulation precede deletion induced by mucosally administered antigen.
Benson JM, Campbell KA, Guan Z, Gienapp IE, Stuckman SS, Forsthuber T, Whitacre CC. T-cell activation and receptor downmodulation precede deletion induced by mucosally administered antigen. J Clin Invest. 2000 Oct; 106(8):1031-8.
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Administration, Oral
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Animals
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Apoptosis
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Clonal Deletion
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Cytokines
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Down-Regulation
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Encephalomyelitis, Autoimmune, Experimental
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Lymphocyte Activation
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Mice
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Mice, Transgenic
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Models, Immunological
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Receptors, Antigen, T-Cell
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Receptors, Antigen, T-Cell, alpha-beta
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Th1 Cells
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Th2 Cells
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Thymectomy
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T-Lymphocytes