Forskolin-inducible cAMP pathway negatively regulates T-cell proliferation by uncoupling the interleukin-2 receptor complex.

Rodriguez G, Ross JA, Nagy ZS, Kirken RA. Forskolin-inducible cAMP pathway negatively regulates T-cell proliferation by uncoupling the interleukin-2 receptor complex. J Biol Chem. 2013 Mar 08; 288(10):7137-46.

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subject areas

1-Methyl-3-isobutylxanthine
Blotting, Western
Cell Cycle Proteins
Cell Line, Tumor
Cell Proliferation
Cyclic AMP
Cyclic AMP-Dependent Protein Kinases
Enzyme Activation
Gene Expression
Humans
Interleukin-2
Interleukin-2 Receptor beta Subunit
Janus Kinase 3
Phosphorylation
Protein Binding
Protein Subunits
Protein Transport
Reverse Transcriptase Polymerase Chain Reaction
Signal Transduction
STAT5 Transcription Factor
T-Lymphocytes

authors with profiles

Georgialina Rodriguez
Robert Kirken

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