Gene expression analysis of tumor spheroids reveals a role for suppressed DNA mismatch repair in multicellular resistance to alkylating agents.

Francia G, Man S, Teicher B, Grasso L, Kerbel RS. Gene expression analysis of tumor spheroids reveals a role for suppressed DNA mismatch repair in multicellular resistance to alkylating agents. Mol Cell Biol. 2004 Aug; 24(15):6837-49.

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subject areas

Alkylating Agents
Animals
Base Pair Mismatch
Base Sequence
Blotting, Northern
Blotting, Western
Cell Line, Tumor
CHO Cells
Cisplatin
Cricetinae
DNA Repair
Dose-Response Relationship, Drug
Drug Resistance, Neoplasm
Female
Gene Expression Profiling
Humans
Mice
Mice, Inbred BALB C
Models, Genetic
Molecular Sequence Data
Oligonucleotide Array Sequence Analysis
Polymerase Chain Reaction
Protein Structure, Tertiary
Reverse Transcriptase Polymerase Chain Reaction
RNA
Sequence Analysis, DNA
Spheroids, Cellular
Time Factors
Transfection
Tumor Cells, Cultured
Up-Regulation

authors with profiles

Giulio Francia

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