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Juwon Park

TitleResearcher
Faculty RankAssistant Professor
InstitutionUniversity of Hawaii
DepartmentTropical Medicine, Medical Microbiology and Pharmacology
AddressJohn A. Burns School of Medicine
University of Hawaii at Manoa
651 Ilalo Street
Honolulu HI 96813
Phone(808) 692-1603
ORCID ORCID Icon0000-0002-9873-0137 Additional info
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    Collapse Biography 
    Collapse education and training
    Kyung Hee University, South KoreaB.S.02/2005 Life Science
    Seoul National University, South KoreaM.S.08/2007Cancer Biology
    Seoul National University, South KoreaPh.D.02/2010Cancer Biology
    Collapse awards and honors
    2021 - 2023CFAR New Investigator Award, University of Washington/NIAID
    2020The Jackson Laboratory workshop scholarship, The Jackson Laboratory
    2018Young scientist Program Fellowship, International Union of Biochemistry and Molecular Biology
    2010Fostering Next-generation Researchers Program,, Korea Student Aid Foundation
    2008National Science and Engineering or Humanities Scholarship, Korea Student Aid Foundation

    Collapse Overview 

    Collapse Research 
    Collapse research activities and funding
    19ADVC-99453     (Juwon Park)Apr 27, 2018 - Jan 31, 2020
    Hawaii Community Foundation
    Roles of PDGFRalpha Fibroblast in Pulmonary Fibrosis
    Role Description: This project is a pilot study to define a subset of activated fibroblast derived from PDGFRalpha fibroblasts and understand their roles in fibrosis progression.
    Role: Principal Investigator

    124-6950-2A     (Juwon Park)Jan 21, 2019 - Dec 31, 2020
    University Hawaii Foundation
    Role: Principal Investigator

    19ADVC-95453     (Juwon Park)May 7, 2019 - Nov 6, 2021
    Hawaii Community Foundation
    Lipofibroblast Regulates Alveolar Development.
    Role Description: This project is a pilot study to understand how lipofibroblasts regulate alveolar type II cells proliferation and differentiation during postnatal lung development.
    Role: Principal Investigator

    K12HL143960     (Cecilia M. Shikuma)Apr 1, 2020 - May 31, 2023
    NIH/NHBLI
    Hawaii Interdisciplinary Mentored Career Development in HIV Co-Morbidities.
    Role: Trainee

    U54MD007601-34     (Juwon Park)Jul 1, 2020 - Jun 30, 2021
    NIH/NIMHD
    The effect of fibroblast ablation on airway remodeling and inflammation in murine asthma.
    Role Description: This project is a pilot study to determine the effect of fibroblast ablation on airway remodeling and inflammation during the progression of asthma.
    Role: Principal Investigator

    UWSC13255     (Juwon Park)Jul 1, 2021 - Jun 30, 2023
    the UW/Fred Hutch Center for AIDS
    Role of neutrophils in HIV­associated thrombosis
    Role Description: This project is to determine neutrophil subsets and whether altered neutrophil activation and interaction of neutrophils with platelets contribute to enhanced thrombosis risk in people living with HIV.
    Role: Principal Investigator

    U54MD007601     (Drs.Devendra and Park)Sep 1, 2022 - May 31, 2027
    NIH/NIMHD
    Factors responsible for the development of pulmonary post-acute sequelae of SARS-CoV-2 infection in Hawaii.
    Role Description: This study will be to elucidate pathophysiologic role of monocytes in the development and persistence of pulmonary Post-Acute Sequelae of SARS-CoV-2 infection and how macro-social and psychological determinants may influence these biological mechanisms.
    Role: Multiple project leader

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Vares-Lum DL, Gangcuangco LMA, Park J, Manzano E, Ortega M, Chow DC, Shikuma C. Plasma galectin-3 is associated with decreased glomerular filtration rate in chronic HIV. HIV Res Clin Pract. 2023 09 20; 24(1):2261753. PMID: 37783570.
      Citations:    Fields:    Translation:Humans
    2. Park J, Dean LS, Heckl J, Gangcuangco LM, Pedro TK, Tallquist MD, Seto TB, Shiramizu B, Chow DC, Shikuma CM. Low-density granulocytes display immature cells with enhanced NET formation in people living with HIV. Sci Rep. 2023 08 16; 13(1):13282. PMID: 37587169.
      Citations: 1     Fields:    Translation:HumansCells
    3. Dean LS, Devendra G, Jiyarom B, Subia N, Tallquist MD, Nerurkar VR, Chang SP, Chow DC, Shikuma CM, Park J. Phenotypic alteration of low-density granulocytes in people with pulmonary post-acute sequalae of SARS-CoV-2 infection. Front Immunol. 2022; 13:1076724. PMID: 36591237.
      Citations:    Fields:    Translation:HumansCells
    4. Dean LS, Chow DC, Ndhlovu LC, Boisvert WA, Chang SP, Shikuma CM, Park J. Characterization of Circulating Fibrocytes in People Living with HIV on Stable Antiretroviral Therapy. Immunohorizons. 2022 11 01; 6(11):760-767. PMID: 36445359.
      Citations: 1     Fields:    Translation:Humans
    5. Kuwabara JT, Hara A, Heckl JR, Pe?a B, Bhutada S, DeMaris R, Ivey MJ, DeAngelo LP, Liu X, Park J, Jahansooz JR, Mestroni L, McKinsey TA, Apte SS, Tallquist MD. Regulation of extracellular matrix composition by fibroblasts during perinatal cardiac maturation. J Mol Cell Cardiol. 2022 08; 169:84-95. PMID: 35569524.
      Citations: 5     Fields:    Translation:AnimalsCells
    6. Park J, Ivey MJ, Deana Y, Riggsbee KL, S?rensen E, Schwabl V, Sj?berg C, Hjertberg T, Park GY, Swonger JM, Rosengreen T, Morty RE, Ahlbrecht K, Tallquist MD. The Tcf21 lineage constitutes the lung lipofibroblast population. Am J Physiol Lung Cell Mol Physiol. 2019 05 01; 316(5):L872-L885. PMID: 30675802.
      Citations: 26     Fields:    Translation:AnimalsCells
    7. Park J, Wysocki RW, Amoozgar Z, Maiorino L, Fein MR, Jorns J, Schott AF, Kinugasa-Katayama Y, Lee Y, Won NH, Nakasone ES, Hearn SA, K?ttner V, Qiu J, Almeida AS, Perurena N, Kessenbrock K, Goldberg MS, Egeblad M. Cancer cells induce metastasis-supporting neutrophil extracellular DNA traps. Sci Transl Med. 2016 10 19; 8(361):361ra138. PMID: 27798263.
      Citations: 388     Fields:    Translation:HumansAnimalsCells
    8. Park J, Bae EK, Lee C, Choi JH, Jung WJ, Ahn KS, Yoon SS. Establishment and characterization of bortezomib-resistant U266 cell line: constitutive activation of NF-?B-mediated cell signals and/or alterations of ubiquitylation-related genes reduce bortezomib-induced apoptosis. BMB Rep. 2014 May; 47(5):274-9. PMID: 24286313.
      Citations: 11     Fields:    Translation:HumansCells
    9. Lee C, Oh JI, Park J, Choi JH, Bae EK, Lee HJ, Jung WJ, Lee DS, Ahn KS, Yoon SS. TNF a mediated IL-6 secretion is regulated by JAK/STAT pathway but not by MEK phosphorylation and AKT phosphorylation in U266 multiple myeloma cells. Biomed Res Int. 2013; 2013:580135. PMID: 24151609.
      Citations: 22     Fields:    Translation:HumansCells
    10. Nakasone ES, Askautrud HA, Kees T, Park JH, Plaks V, Ewald AJ, Fein M, Rasch MG, Tan YX, Qiu J, Park J, Sinha P, Bissell MJ, Frengen E, Werb Z, Egeblad M. Imaging tumor-stroma interactions during chemotherapy reveals contributions of the microenvironment to resistance. Cancer Cell. 2012 Apr 17; 21(4):488-503. PMID: 22516258.
      Citations: 249     Fields:    Translation:AnimalsCells
    11. Park J, Bae E, Lee C, Yoon SS, Chae YS, Ahn KS, Won NH. RNA interference-directed caveolin-1 knockdown sensitizes SN12CPM6 cells to doxorubicin-induced apoptosis and reduces lung metastasis. Tumour Biol. 2010 Dec; 31(6):643-50. PMID: 20820979.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    12. Park J, Kim KI, Koh Y, Won NH, Oh JM, Lee DS, Kim BK, Ahn KS, Yoon SS. Establishment of a new Glivec-resistant chronic myeloid leukemia cell line, SNUCML-02, using an in vivo model. Exp Hematol. 2010 Sep; 38(9):773-81. PMID: 20438801.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    13. Kim KI, Park J, Ahn KS, Won NH, Kim BK, Shin WG, Yoon SS, Oh JM. Molecular characterization and prognostic significance of FLT3 in CML progression. Leuk Res. 2010 Aug; 34(8):995-1001. PMID: 20031210.
      Citations: 4     Fields:    Translation:HumansCells
    14. Koh Y, Park J, Bae EK, Ahn KS, Kim I, Bang SM, Lee JH, Yoon SS, Lee DS, Lee YY, Park S, Kim BK. Non-A type nucleophosmin 1 gene mutation predicts poor clinical outcome in de novo adult acute myeloid leukemia: differential clinical importance of NPM1 mutation according to subtype. Int J Hematol. 2009 Jul; 90(1):1-5. PMID: 19484332.
      Citations: 16     Fields:    Translation:Humans
    15. Koh Y, Park J, Ahn KS, Kim I, Bang SM, Lee JH, Yoon SS, Soon Lee D, Yiul Lee Y, Park S, Kim BK. Different clinical importance of FLT3 internal tandem duplications in AML according to FAB classification: possible existence of distinct leukemogenesis involving monocyte differentiation pathway. Ann Hematol. 2009 Nov; 88(11):1089-97. PMID: 19296110.
      Citations: 6     Fields:    Translation:HumansCells
    16. Park J, Ayyappan V, Bae EK, Lee C, Kim BS, Kim BK, Lee YY, Ahn KS, Yoon SS. Curcumin in combination with bortezomib synergistically induced apoptosis in human multiple myeloma U266 cells. Mol Oncol. 2008 Dec; 2(4):317-26. PMID: 19383353.
      Citations: 28     Fields:    Translation:HumansCells
    17. Park J, Ahn KS, Bae EK, Kim BS, Kim BK, Lee YY, Yoon SS. Blockage of interleukin-6 signaling with 6-amino-4-quinazoline synergistically induces the inhibitory effect of bortezomib in human U266 cells. Anticancer Drugs. 2008 Sep; 19(8):777-82. PMID: 18690088.
      Citations: 7     Fields:    Translation:HumansCells
    18. Kim BS, Bae E, Kim YJ, Ahn KS, Park J, Rhee JY, Lee YY, Kim Y, Lee D, Kim BK, Yoon SS. Combination of SK-7041, one of novel histone deacetylase inhibitors, and STI571-induced synergistic apoptosis in chronic myeloid leukemia. Anticancer Drugs. 2007 Jul; 18(6):641-7. PMID: 17762392.
      Citations: 3     Fields:    Translation:HumansCells
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