Apoptotic Protease-Activating Factor 1
"Apoptotic Protease-Activating Factor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A CARD signaling adaptor protein characterized by an N-terminal CARD DOMAIN and C-terminal WD40 REPEATS. It plays a role in the mitochondria-stimulated apoptosis (APOPTOSIS, INTRINSIC PATHWAY) and binds to CYTOCHROME C in the CYTOSOL to form an APOPTOSOMAL PROTEIN COMPLEX which activates INITIATOR CASPASES such as CASPASE 9.
| Descriptor ID |
D053477
|
| MeSH Number(s) |
D12.644.360.024.131.124 D12.644.360.075.358.124 D12.776.157.057.006.124 D12.776.476.024.139.124 D12.776.476.075.358.124
|
| Concept/Terms |
Apoptotic Protease-Activating Factor 1- Apoptotic Protease-Activating Factor 1
- Apoptotic Protease Activating Factor 1
- Apaf-1 Protease-Activating Factor
- Apaf 1 Protease Activating Factor
- Protease-Activating Factor, Apaf-1
- Apoptotic Peptidase Activating Factor 1
|
Below are MeSH descriptors whose meaning is more general than "Apoptotic Protease-Activating Factor 1".
Below are MeSH descriptors whose meaning is more specific than "Apoptotic Protease-Activating Factor 1".
This graph shows the total number of publications written about "Apoptotic Protease-Activating Factor 1" by people in this website by year, and whether "Apoptotic Protease-Activating Factor 1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Apoptotic Protease-Activating Factor 1" by people in Profiles.
-
Yang S, Liu J, Thor AD, Yang X. Caspase expression profile and functional activity in a panel of breast cancer cell lines. Oncol Rep. 2007 May; 17(5):1229-35.
-
Cao G, Xiao M, Sun F, Xiao X, Pei W, Li J, Graham SH, Simon RP, Chen J. Cloning of a novel Apaf-1-interacting protein: a potent suppressor of apoptosis and ischemic neuronal cell death. J Neurosci. 2004 Jul 07; 24(27):6189-201.