Receptors, G-Protein-Coupled

"Receptors, G-Protein-Coupled" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The largest family of cell surface receptors involved in SIGNAL TRANSDUCTION. They share a common structure and signal through HETEROTRIMERIC G-PROTEINS.

Descriptor ID	D043562
MeSH Number(s)	D12.776.543.750.695
Concept/Terms	Receptors, G-Protein-Coupled Receptors, G-Protein-Coupled Receptors, G Protein Coupled G-Protein-Coupled Receptors G Protein Coupled Receptors

Below are MeSH descriptors whose meaning is more general than "Receptors, G-Protein-Coupled".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, G-Protein-Coupled [D12.776.543.750.695]

Below are MeSH descriptors whose meaning is related to "Receptors, G-Protein-Coupled".

Below are MeSH descriptors whose meaning is more specific than "Receptors, G-Protein-Coupled".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Receptors, G-Protein-Coupled" by people in this website by year, and whether "Receptors, G-Protein-Coupled" was a major or minor topic of these publications.

Bar chart showing 75 publications over 24 distinct years, with a maximum of 6 publications in 2013 and 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	1	0	1
2000	1	0	1
2001	1	2	3
2002	0	1	1
2004	3	2	5
2005	1	0	1
2006	1	0	1
2007	1	2	3
2008	1	1	2
2009	0	1	1
2010	1	4	5
2011	1	2	3
2012	3	1	4
2013	5	1	6
2014	3	2	5
2015	2	2	4
2016	1	0	1
2017	3	1	4
2018	3	3	6
2019	2	1	3
2020	1	3	4
2021	5	0	5
2022	1	1	2
2024	2	2	4

Below are the most recent publications written about "Receptors, G-Protein-Coupled" by people in Profiles.

Hanafi D, Onyenwoke RU, Kimbro KS. The G-Protein-Coupled Estrogen Receptor Selective Agonist G-1 Attenuates Cell Viability and Migration in High-Grade Serous Ovarian Cancer Cell Lines. Int J Mol Sci. 2024 Jun 13; 25(12).

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Hixon JC, Rivas Zarete JI, White J, Hilaire M, Muhammad A, Yusuf AP, Adu-Addai B, Yates CC, Mahavadi S. Epigenetic Modulation of GPER Expression in Gastric and Colonic Smooth Muscle of Male and Female Non-Obese Diabetic (NOD) Mice: Insights into H3K4me3 and H3K27ac Modifications. Int J Mol Sci. 2024 May 11; 25(10).

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Muhammad A, Hixon JC, Pharmacy Yusuf A, Rivas Zarete JI, Johnson I, Miller J, Adu-Addai B, Yates C, Mahavadi S. Sex-specific epigenetics drive low GPER expression in gastrointestinal smooth muscles in type 2 diabetic mice. Sci Rep. 2024 03 07; 14(1):5633.

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Huang BZ, Binder AM, Quon B, Patel YM, Lum-Jones A, Tiirikainen M, Murphy SE, Loo L, Maunakea AK, Haiman CA, Wilkens LR, Koh WP, Cai Q, Aldrich MC, Siegmund KD, Hecht SS, Yuan JM, Blot WJ, Stram DO, Le Marchand L, Park SL. Epigenome-wide association study of total nicotine equivalents in multiethnic current smokers from three prospective cohorts. Am J Hum Genet. 2024 03 07; 111(3):456-472.

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Dankwah KO, Mohl JE, Begum K, Leung MY. What Makes GPCRs from Different Families Bind to the Same Ligand? Biomolecules. 2022 06 21; 12(7).

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Zha XM, Xiong ZG, Simon RP. pH and proton-sensitive receptors in brain ischemia. J Cereb Blood Flow Metab. 2022 08; 42(8):1349-1363.

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Zhang S, Wang H, Melick CH, Jeong MH, Curukovic A, Tiwary S, Lama-Sherpa TD, Meng D, Servage KA, James NG, Jewell JL. AKAP13 couples GPCR signaling to mTORC1 inhibition. PLoS Genet. 2021 10; 17(10):e1009832.

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Shah A, Ratkowski M, Rosa A, Feinstein P, Bozza T. Olfactory expression of trace amine-associated receptors requires cooperative cis-acting enhancers. Nat Commun. 2021 06 18; 12(1):3797.

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Lu J, Chen PP, Zhang JX, Li XQ, Wang GH, Yuan BY, Huang SJ, Liu XQ, Jiang TT, Wang MY, Liu WT, Ruan XZ, Liu BC, Ma KL. GPR43 deficiency protects against podocyte insulin resistance in diabetic nephropathy through the restoration of AMPKa activity. Theranostics. 2021; 11(10):4728-4742.

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Liang H, Matei N, McBride DW, Xu Y, Zhou Z, Tang J, Luo B, Zhang JH. TGR5 activation attenuates neuroinflammation via Pellino3 inhibition of caspase-8/NLRP3 after middle cerebral artery occlusion in rats. J Neuroinflammation. 2021 Feb 02; 18(1):40.

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