Receptors, Formyl Peptide
"Receptors, Formyl Peptide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of G-protein-coupled receptors that was originally identified by its ability to bind N-formyl peptides such as N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE. Since N-formyl peptides are found in MITOCHONDRIA and BACTERIA, this class of receptors is believed to play a role in mediating cellular responses to cellular damage and bacterial invasion. However, non-formylated peptide ligands have also been found for this receptor class.
| Descriptor ID |
D044042
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| MeSH Number(s) |
D12.776.543.750.695.235 D12.776.543.750.705.873 D12.776.543.750.750.340
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| Concept/Terms |
Receptors, Formyl Peptide- Receptors, Formyl Peptide
- Formyl Peptide Receptors
- Peptide Receptors, Formyl
- FMLP Receptor
- Receptor, FMLP
- N-formyl Hexapeptide Receptor
- Hexapeptide Receptor, N-formyl
- N formyl Hexapeptide Receptor
- Receptor, N-formyl Hexapeptide
- N-Formylmethionyl Peptide Receptor
- N Formylmethionyl Peptide Receptor
- Peptide Receptor, N-Formylmethionyl
- Receptor, N-Formylmethionyl Peptide
- fMet-Leu-Phe Receptor
- Receptor, fMet-Leu-Phe
- fMet Leu Phe Receptor
- Formyl Peptide Receptor
- Receptor, Formyl Peptide
- Receptor, Chemotactic Peptide
- Chemotactic Peptide Receptor
- Peptide Receptor, Chemotactic
- F-Chemotactic Peptide Receptor
- F Chemotactic Peptide Receptor
- Receptor, F-Chemotactic Peptide
- Chemoattractant Receptor
- Receptor, Chemoattractant
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Below are MeSH descriptors whose meaning is more general than "Receptors, Formyl Peptide".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Formyl Peptide".
This graph shows the total number of publications written about "Receptors, Formyl Peptide" by people in this website by year, and whether "Receptors, Formyl Peptide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 1 | 2 |
| 2005 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, Formyl Peptide" by people in Profiles.
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Key TA, Vines CM, Wagener BM, Gurevich VV, Sklar LA, Prossnitz ER. Inhibition of chemoattractant N-formyl peptide receptor trafficking by active arrestins. Traffic. 2005 Feb; 6(2):87-99.
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Xue M, Vines CM, Buranda T, Cimino DF, Bennett TA, Prossnitz ER. N-formyl peptide receptors cluster in an active raft-associated state prior to phosphorylation. J Biol Chem. 2004 Oct 22; 279(43):45175-84.
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Revankar CM, Vines CM, Cimino DF, Prossnitz ER. Arrestins block G protein-coupled receptor-mediated apoptosis. J Biol Chem. 2004 Jun 04; 279(23):24578-84.
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Vines CM, Revankar CM, Maestas DC, LaRusch LL, Cimino DF, Kohout TA, Lefkowitz RJ, Prossnitz ER. N-formyl peptide receptors internalize but do not recycle in the absence of arrestins. J Biol Chem. 2003 Oct 24; 278(43):41581-4.
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Vines CM, Xue M, Maestas DC, Cimino DF, Prossnitz ER. Regulation of N-formyl peptide-mediated degranulation by receptor phosphorylation. J Immunol. 2002 Dec 15; 169(12):6760-6.