rhoA GTP-Binding Protein

"rhoA GTP-Binding Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A RHO GTP-BINDING PROTEIN involved in regulating signal transduction pathways that control assembly of focal adhesions and actin stress fibers. This enzyme was formerly listed as EC 3.6.1.47.

Descriptor ID	D020742
MeSH Number(s)	D08.811.277.040.330.300.400.700.200 D12.644.360.525.700.200 D12.776.157.325.515.700.200 D12.776.476.525.700.200
Concept/Terms	rhoA GTP-Binding Protein rhoA GTP-Binding Protein GTP-Binding Protein, rhoA rhoA GTP Binding Protein rhoA P21 Protein rho12 Protein ARHA GTP-Binding Protein ARHA GTP Binding Protein GTP-Binding Protein, ARHA rhoA Protein Ras Homolog Family Member A rho12 GTP-Binding Protein GTP-Binding Protein, rho12 rho12 GTP Binding Protein V14rho V14rho V14rhoA

Below are MeSH descriptors whose meaning is more general than "rhoA GTP-Binding Protein".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Hydrolases [D08.811.277]
Acid Anhydride Hydrolases [D08.811.277.040]
GTP Phosphohydrolases [D08.811.277.040.330]
GTP-Binding Proteins [D08.811.277.040.330.300]
Monomeric GTP-Binding Proteins [D08.811.277.040.330.300.400]
rho GTP-Binding Proteins [D08.811.277.040.330.300.400.700]
rhoA GTP-Binding Protein [D08.811.277.040.330.300.400.700.200]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Monomeric GTP-Binding Proteins [D12.644.360.525]
rho GTP-Binding Proteins [D12.644.360.525.700]
rhoA GTP-Binding Protein [D12.644.360.525.700.200]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
GTP-Binding Proteins [D12.776.157.325]
Monomeric GTP-Binding Proteins [D12.776.157.325.515]
rho GTP-Binding Proteins [D12.776.157.325.515.700]
rhoA GTP-Binding Protein [D12.776.157.325.515.700.200]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Monomeric GTP-Binding Proteins [D12.776.476.525]
rho GTP-Binding Proteins [D12.776.476.525.700]
rhoA GTP-Binding Protein [D12.776.476.525.700.200]

Below are MeSH descriptors whose meaning is related to "rhoA GTP-Binding Protein".

Below are MeSH descriptors whose meaning is more specific than "rhoA GTP-Binding Protein".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "rhoA GTP-Binding Protein" by people in this website by year, and whether "rhoA GTP-Binding Protein" was a major or minor topic of these publications.

Bar chart showing 24 publications over 18 distinct years, with a maximum of 2 publications in 2003 and 2007 and 2013 and 2016 and 2017 and 2025

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	0	1	1
2002	0	1	1
2003	2	0	2
2004	1	0	1
2005	1	0	1
2006	1	0	1
2007	1	1	2
2008	0	1	1
2009	1	0	1
2010	0	1	1
2011	1	0	1
2013	0	2	2
2016	2	0	2
2017	0	2	2
2018	1	0	1
2019	1	0	1
2024	1	0	1
2025	2	0	2

Below are the most recent publications written about "rhoA GTP-Binding Protein" by people in Profiles.

Pal A, Bawali P, Brahma A, Rana SR, Mohapatra R, Chakraborty D, Poirah I, Samal S, Banerjee S, Smoot DT, Ashktorab H, Bhattacharyya A. RHOA-dependent regulation of mitochondrial remodeling and cell motility in hypoxia-exposed gastric epithelial cells. J Cell Sci. 2025 Jul 15; 138(14).

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Marikawa Y, Alarcon VB. Regulation of trophectoderm morphogenesis by small GTPase RHOA through HIPPO signaling-dependent and -independent mechanisms in mouse preimplantation development. Differentiation. 2025 Jan-Feb; 141:100835.

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He Q, Zhou Y, Wu L, Huang L, Yuan Y, Flores JJ, Luo X, Tao Y, Chen X, Kanamaru H, Dong S, Zhu S, Yu Q, Han M, Sherchan P, Li J, Tang J, Xie Z, Zhang JH. Inhibition of acid-sensing receptor GPR4 attenuates neuronal ferroptosis via RhoA/YAP signaling in a rat model of subarachnoid hemorrhage. Free Radic Biol Med. 2024 Nov 20; 225:333-345.

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Marikawa Y, Alarcon VB. RHOA activity in expanding blastocysts is essential to regulate HIPPO-YAP signaling and to maintain the trophectoderm-specific gene expression program in a ROCK/actin filament-independent manner. Mol Hum Reprod. 2019 02 01; 25(2):43-60.

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Yu OM, Benitez JA, Plouffe SW, Ryback D, Klein A, Smith J, Greenbaum J, Delatte B, Rao A, Guan KL, Furnari FB, Chaim OM, Miyamoto S, Brown JH. YAP and MRTF-A, transcriptional co-activators of RhoA-mediated gene expression, are critical for glioblastoma tumorigenicity. Oncogene. 2018 10; 37(41):5492-5507.

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Scarlett KA, White EZ, Coke CJ, Carter JR, Bryant LK, Hinton CV. Agonist-induced CXCR4 and CB2 Heterodimerization Inhibits Ga13/RhoA-mediated Migration. Mol Cancer Res. 2018 04; 16(4):728-739.

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Fan R, Enkhjargal B, Camara R, Yan F, Gong L, Tang J, Chen Y, Zhang JH. Critical role of EphA4 in early brain injury after subarachnoid hemorrhage in rat. Exp Neurol. 2017 10; 296:41-48.

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Ntantie E, Fletcher J, Amissah F, Salako OO, Nkembo AT, Poku RA, Ikpatt FO, Lamango NS. Polyisoprenylated cysteinyl amide inhibitors disrupt actin cytoskeleton organization, induce cell rounding and block migration of non-small cell lung cancer. Oncotarget. 2017 May 09; 8(19):31726-31744.

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Maldonado H, Calderon C, Burgos-Bravo F, Kobler O, Zuschratter W, Ramirez O, H?rtel S, Schneider P, Quest AF, Herrera-Molina R, Leyton L. Astrocyte-to-neuron communication through integrin-engaged Thy-1/CBP/Csk/Src complex triggers neurite retraction via the RhoA/ROCK pathway. Biochim Biophys Acta Mol Cell Res. 2017 Feb; 1864(2):243-254.

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Zhao H, Zhang X, Dai Z, Feng Y, Li Q, Zhang JH, Liu X, Chen Y, Feng H. P2X7 Receptor Suppression Preserves Blood-Brain Barrier through Inhibiting RhoA Activation after Experimental Intracerebral Hemorrhage in Rats. Sci Rep. 2016 Mar 16; 6:23286.

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