"GTP-Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Regulatory proteins that act as molecular switches. They control a wide range of biological processes including: receptor signaling, intracellular signal transduction pathways, and protein synthesis. Their activity is regulated by factors that control their ability to bind to and hydrolyze GTP to GDP. EC 3.6.1.-.
| Descriptor ID |
D019204
|
| MeSH Number(s) |
D08.811.277.040.330.300 D12.776.157.325
|
| Concept/Terms |
GTP-Binding Proteins- GTP-Binding Proteins
- GTP Binding Proteins
- Proteins, GTP-Binding
- G-Proteins
- G Proteins
- GTP-Binding Protein
- GTP Binding Protein
- Protein, GTP-Binding
- Guanine Nucleotide Regulatory Proteins
- GTP-Regulatory Protein
- GTP Regulatory Protein
- Protein, GTP-Regulatory
- GTP-Regulatory Proteins
- GTP Regulatory Proteins
- Proteins, GTP-Regulatory
- Guanine Nucleotide Coupling Protein
- G-Protein
- G Protein
|
Below are MeSH descriptors whose meaning is more general than "GTP-Binding Proteins".
Below are MeSH descriptors whose meaning is more specific than "GTP-Binding Proteins".
This graph shows the total number of publications written about "GTP-Binding Proteins" by people in this website by year, and whether "GTP-Binding Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1996 | 0 | 2 | 2 |
| 1997 | 1 | 0 | 1 |
| 1998 | 1 | 2 | 3 |
| 1999 | 3 | 0 | 3 |
| 2000 | 3 | 1 | 4 |
| 2001 | 1 | 0 | 1 |
| 2002 | 4 | 2 | 6 |
| 2003 | 1 | 1 | 2 |
| 2004 | 2 | 1 | 3 |
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 2 | 1 | 3 |
| 2011 | 1 | 2 | 3 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 1 | 2 |
| 2015 | 2 | 0 | 2 |
| 2016 | 1 | 1 | 2 |
| 2017 | 1 | 1 | 2 |
| 2018 | 2 | 3 | 5 |
| 2022 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "GTP-Binding Proteins" by people in Profiles.
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Namballa HK, Dorogan M, Gudipally AR, Okafor S, Gadhiya S, Harding WW. Discovery of Selective Dopamine Receptor Ligands Derived from (-)-Stepholidine via C-3 Alkoxylation and C-3/C-9 Dialkoxylation. J Med Chem. 2023 07 27; 66(14):10060-10079.
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Medina JI, Cruz-Collazo A, Del Mar Maldonado M, Gascot TM, Borrero-Garcia LD, Cooke M, Kazanietz MG, O'Farril EH, Vlaar CP, Dharmawardhane S. Characterization of Novel Derivatives of MBQ-167, an inhibitor of the GTP-binding proteins Rac/Cdc42. Cancer Res Commun. 2022 12; 2(12):1711-1726.
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Rajarathnam K, Schnoor M, Richardson RM, Rajagopal S. How do chemokines navigate neutrophils to the target site: Dissecting the structural mechanisms and signaling pathways. Cell Signal. 2019 02; 54:69-80.
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Jagla CAD, Scott CE, Tang Y, Qiao C, Mateo-Semidey GE, Yudowski GA, Lu D, Kendall DA. Pyrimidinyl Biphenylureas Act as Allosteric Modulators to Activate Cannabinoid Receptor 1 and Initiate ?-Arrestin-Dependent Responses. Mol Pharmacol. 2019 01; 95(1):1-10.
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Pathak P, Xie C, Nichols RG, Ferrell JM, Boehme S, Krausz KW, Patterson AD, Gonzalez FJ, Chiang JYL. Intestine farnesoid X receptor agonist and the gut microbiota activate G-protein bile acid receptor-1 signaling to improve metabolism. Hepatology. 2018 10; 68(4):1574-1588.
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Zheng S, Dong F, Rasul F, Yao X, Jin QW, Zheng F, Fu C. Septins regulate the equatorial dynamics of the separation initiation network kinase Sid2p and glucan synthases to ensure proper cytokinesis. FEBS J. 2018 07; 285(13):2468-2480.
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Kabbani N, Nichols RA. Beyond the Channel: Metabotropic Signaling by Nicotinic Receptors. Trends Pharmacol Sci. 2018 04; 39(4):354-366.
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Nogueras-Ortiz C, Roman-Vendrell C, Mateo-Semidey GE, Liao YH, Kendall DA, Yudowski GA. Retromer stops beta-arrestin 1-mediated signaling from internalized cannabinoid 2 receptors. Mol Biol Cell. 2017 Nov 15; 28(24):3554-3561.
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Matsumoto I, Uchida K, Nakashima K, Hiyoshi S, Chambers JK, Tsujimoto H, Nakayama H. IgA Antibodies Against Gliadin and Tissue Transglutaminase in Dogs With Chronic Enteritis and Intestinal T-Cell Lymphoma. Vet Pathol. 2018 01; 55(1):98-107.
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Movahedi K, Grosmaitre X, Feinstein P. Odorant receptors can mediate axonal identity and gene choice via cAMP-independent mechanisms. Open Biol. 2016 07; 6(7).