A mass spectrometric technique that is used for the analysis of large biomolecules. Analyte molecules are embedded in an excess matrix of small organic molecules that show a high resonant absorption at the laser wavelength used. The matrix absorbs the laser energy, thus inducing a soft disintegration of the sample-matrix mixture into free (gas phase) matrix and analyte molecules and molecular ions. In general, only molecular ions of the analyte molecules are produced, and almost no fragmentation occurs. This makes the method well suited for molecular weight determinations and mixture analysis.

Descriptor ID	D019032
MeSH Number(s)	E05.196.566.755
Concept/Terms	Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry, Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry, Matrix Assisted Laser Desorption Ionization Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry Matrix Assisted Laser Desorption Ionization Mass Spectrometry MALDI Spectroscopy, Mass, Matrix-Assisted Laser Desorption-Ionization MS-MALD MALD-MS MALDI-MS MALDI MS Laser Desorption-Ionization Mass Spectrometry, Matrix-Assisted Laser Desorption Ionization Mass Spectrometry, Matrix Assisted Mass Spectroscopy, Matrix-Assisted Laser Desorption-Ionization Mass Spectroscopy, Matrix Assisted Laser Desorption Ionization Surface Enhanced Laser Desorption Ionization Mass Spectrometry Surface Enhanced Laser Desorption Ionization Mass Spectrometry SELDI-TOF-MS

Below are MeSH descriptors whose meaning is more general than "Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization".

Below are MeSH descriptors whose meaning is related to "Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization".

Below are MeSH descriptors whose meaning is more specific than "Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization".