Transcription Factor AP-1
"Transcription Factor AP-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multiprotein complex composed of the products of c-jun and c-fos proto-oncogenes. These proteins must dimerize in order to bind to the AP-1 recognition site, also known as the TPA-responsive element (TRE). AP-1 controls both basal and inducible transcription of several genes.
| Descriptor ID |
D018808
|
| MeSH Number(s) |
D12.776.260.108.875 D12.776.930.127.875
|
| Concept/Terms |
Transcription Factor AP-1- Transcription Factor AP-1
- Transcription Factor AP 1
- AP-1 Enhancer-Binding Protein
- Enhancer-Binding Protein, AP-1
- AP-1
- Activator Protein-1
- Activator Protein 1
- AP-1 Enhancer Binding Protein
- AP 1 Enhancer Binding Protein
|
Below are MeSH descriptors whose meaning is more general than "Transcription Factor AP-1".
Below are MeSH descriptors whose meaning is more specific than "Transcription Factor AP-1".
This graph shows the total number of publications written about "Transcription Factor AP-1" by people in this website by year, and whether "Transcription Factor AP-1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1997 | 1 | 1 | 2 |
| 1998 | 1 | 2 | 3 |
| 2002 | 1 | 0 | 1 |
| 2003 | 0 | 1 | 1 |
| 2006 | 2 | 3 | 5 |
| 2007 | 2 | 0 | 2 |
| 2008 | 2 | 0 | 2 |
| 2009 | 1 | 1 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 2 | 2 | 4 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2015 | 0 | 2 | 2 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Transcription Factor AP-1" by people in Profiles.
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Jameson NM, Ma J, Benitez J, Izurieta A, Han JY, Mendez R, Parisian A, Furnari F. Intron 1-Mediated Regulation of EGFR Expression in EGFR-Dependent Malignancies Is Mediated by AP-1 and BET Proteins. Mol Cancer Res. 2019 11; 17(11):2208-2220.
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Jung SK, Ha SJ, Jung CH, Kim YT, Lee HK, Kim MO, Lee MH, Mottamal M, Bode AM, Lee KW, Dong Z. Naringenin targets ERK2 and suppresses UVB-induced photoaging. J Cell Mol Med. 2016 May; 20(5):909-19.
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Kumar NV, Yang J, Pillai JK, Rawat S, Solano C, Kumar A, Gr?tli M, Stemmler TL, Rosen BP, Tam?s MJ. Arsenic Directly Binds to and Activates the Yeast AP-1-Like Transcription Factor Yap8. Mol Cell Biol. 2015 Dec 28; 36(6):913-22.
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West RJ, Lu Y, Marie B, Gao FB, Sweeney ST. Rab8, POSH, and TAK1 regulate synaptic growth in a Drosophila model of frontotemporal dementia. J Cell Biol. 2015 Mar 30; 208(7):931-47.
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Nookala AR, Shah A, Noel RJ, Kumar A. HIV-1 Tat-mediated induction of CCL5 in astrocytes involves NF-?B, AP-1, C/EBPa and C/EBP? transcription factors and JAK, PI3K/Akt and p38 MAPK signaling pathways. PLoS One. 2013; 8(11):e78855.
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Higa JK, Liang Z, Williams PG, Panee J. Phyllostachys edulis compounds inhibit palmitic acid-induced monocyte chemoattractant protein 1 (MCP-1) production. PLoS One. 2012; 7(9):e45082.
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Zhou YW, Munoz J, Jiang D, Jarrett HW. Laminin-a1 LG4-5 domain binding to dystroglycan mediates muscle cell survival, growth, and the AP-1 and NF-?B transcription factors but also has adverse effects. Am J Physiol Cell Physiol. 2012 Mar 15; 302(6):C902-14.
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Li J, Mottamal M, Li H, Liu K, Zhu F, Cho YY, Sosa CP, Zhou K, Bowden GT, Bode AM, Dong Z. Quercetin-3-methyl ether suppresses proliferation of mouse epidermal JB6 P+ cells by targeting ERKs. Carcinogenesis. 2012 Feb; 33(2):459-65.
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Jiang D, Jia Y, Jarrett HW. Transcription factor proteomics: identification by a novel gel mobility shift-three-dimensional electrophoresis method coupled with southwestern blot and high-performance liquid chromatography-electrospray-mass spectrometry analysis. J Chromatogr A. 2011 Sep 28; 1218(39):7003-15.
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Higa JK, Panee J. Bamboo extract reduces interleukin 6 (IL-6) overproduction under lipotoxic conditions through inhibiting the activation of NF-?B and AP-1 pathways. Cytokine. 2011 Jul; 55(1):18-23.