Virus Latency

"Virus Latency" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The ability of a pathogenic virus to lie dormant within a cell (latent infection). In eukaryotes, subsequent activation and viral replication is thought to be caused by extracellular stimulation of cellular transcription factors. Latency in bacteriophage is maintained by the expression of virally encoded repressors.

Descriptor ID	D017735
MeSH Number(s)	G06.920.900
Concept/Terms	Virus Latency Virus Latency Latencies, Virus Latency, Virus Virus Latencies Viral Latency Latencies, Viral Latency, Viral Viral Latencies

Below are MeSH descriptors whose meaning is more general than "Virus Latency".

Biological Sciences [G]
Microbiological Phenomena [G06]
Virus Physiological Phenomena [G06.920]
Virus Latency [G06.920.900]

Below are MeSH descriptors whose meaning is related to "Virus Latency".

Below are MeSH descriptors whose meaning is more specific than "Virus Latency".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Virus Latency" by people in this website by year, and whether "Virus Latency" was a major or minor topic of these publications.

Bar chart showing 39 publications over 19 distinct years, with a maximum of 4 publications in 2003 and 2008 and 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	1	1
2003	2	2	4
2006	1	0	1
2007	0	1	1
2008	3	1	4
2009	1	1	2
2010	0	2	2
2011	3	0	3
2012	2	0	2
2013	1	0	1
2015	0	1	1
2016	2	0	2
2017	1	1	2
2019	0	4	4
2020	0	1	1
2021	0	2	2
2023	0	2	2
2024	0	2	2
2025	1	1	2

Below are the most recent publications written about "Virus Latency" by people in Profiles.

Atkins A, Ndhlovu LC, Furler O'Brien RL. Illuminating lymphoid tissue HIV reservoirs: advanced assays and their relevance to achieving an HIV cure. Curr Opin HIV AIDS. 2025 Nov 01; 20(6):533-542.

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Ehrenberg PK, Geretz A, Volcic M, Izumi T, Yum LK, Waickman A, Shangguan S, Paquin-Proulx D, Creegan M, Bose M, Machmach K, McGraw A, Narahari A, Currier JR, Sacdalan C, Phanuphak N, Apps R, Corley M, Ndhlovu LC, Slike B, Krebs SJ, Anonworanich J, Tovanabutra S, Robb ML, Eller MA, Laird GM, Cyktor J, Daar ES, Crowell TA, Mellors JW, Vasan S, Michael NL, Kirchhoff F, Thomas R. Single-cell analyses identify monocyte gene expression profiles that influence HIV-1 reservoir size in acutely treated cohorts. Nat Commun. 2025 May 29; 16(1):4975.

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Prigann J, Tavora R, Furler O'Brien RL, Schulze-Gahmen U, Boehm D, Roan NR, Nixon DF, Ndhlovu LC, Valente S, Ott M. Silencing the transcriptionally active HIV reservoir to improve treatment outcomes. Nat Microbiol. 2024 Oct; 9(10):2470-2472.

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Yang S, Cao D, Jaijyan DK, Wang M, Liu J, Cruz-Cosme R, Wu S, Huang J, Zeng M, Liu X, Sun W, Xiong D, Tang Q, Xiao L, Zhu H. Identification and characterization of Varicella Zoster Virus circular RNA in lytic infection. Nat Commun. 2024 Jun 10; 15(1):4932.

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Lyons DE, Kumar P, Roan NR, Defechereux PA, Feschotte C, Lange UC, Murthy N, Sameshima P, Verdin E, Ake JA, Parsons MS, Nath A, Gianella S, Smith DM, Kallas EG, Villa TJ, Strange R, Mwesigwa B, Furler O'Brien RL, Nixon DF, Ndhlovu LC, Valente ST, Ott M. HIV-1 Remission: Accelerating the Path to Permanent HIV-1 Silencing. Viruses. 2023 10 28; 15(11).

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Moar P, Premeaux TA, Atkins A, Ndhlovu LC. The latent HIV reservoir: current advances in genetic sequencing approaches. mBio. 2023 10 31; 14(5):e0134423.

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Corley MJ, Pang APS, Rasmussen TA, Tolstrup M, S?gaard OS, Ndhlovu LC. Candidate host epigenetic marks predictive for HIV reservoir size, responsiveness to latency reversal, and viral rebound. AIDS. 2021 11 15; 35(14):2269-2279.

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Shytaj IL, Procopio FA, Tarek M, Carlon-Andres I, Tang HY, Goldman AR, Munshi M, Kumar Pal V, Forcato M, Sreeram S, Leskov K, Ye F, Lucic B, Cruz N, Ndhlovu LC, Bicciato S, Padilla-Parra S, Diaz RS, Singh A, Lusic M, Karn J, Alvarez-Carbonell D, Savarino A. Glycolysis downregulation is a hallmark of HIV-1 latency and sensitizes infected cells to oxidative stress. EMBO Mol Med. 2021 08 09; 13(8):e13901.

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Zhang Q, Martin-Caraballo M, Hsia SV. Modulation of Voltage-Gated Sodium Channel Activity in Human Dorsal Root Ganglion Neurons by Herpesvirus Quiescent Infection. J Virol. 2020 01 17; 94(3).

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Mitchell BI, Laws EI, Ndhlovu LC. Impact of Myeloid Reservoirs in HIV Cure Trials. Curr HIV/AIDS Rep. 2019 04; 16(2):129-140.

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