"Interleukin-11" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A lymphohematopoietic cytokine that plays a role in regulating the proliferation of ERYTHROID PRECURSOR CELLS. It induces maturation of MEGAKARYOCYTES which results in increased production of BLOOD PLATELETS. Interleukin-11 was also initially described as an inhibitor of ADIPOGENESIS of cultured preadipocytes.
| Descriptor ID |
D017370
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| MeSH Number(s) |
D12.644.276.374.465.511 D12.776.467.374.465.511 D23.529.374.465.511
|
| Concept/Terms |
Interleukin-11- Interleukin-11
- Interleukin 11
- IL-11
- IL11
- Adipogenesis Inhibitory Factor
- Factor, Adipogenesis Inhibitory
- Inhibitory Factor, Adipogenesis
|
Below are MeSH descriptors whose meaning is more general than "Interleukin-11".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-11".
This graph shows the total number of publications written about "Interleukin-11" by people in this website by year, and whether "Interleukin-11" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1997 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
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Below are the most recent publications written about "Interleukin-11" by people in Profiles.
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Kilroy GE, Foster SJ, Wu X, Ruiz J, Sherwood S, Heifetz A, Ludlow JW, Stricker DM, Potiny S, Green P, Halvorsen YD, Cheatham B, Storms RW, Gimble JM. Cytokine profile of human adipose-derived stem cells: expression of angiogenic, hematopoietic, and pro-inflammatory factors. J Cell Physiol. 2007 Sep; 212(3):702-9.
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Zhang Y, Taveggia C, Melendez-Vasquez C, Einheber S, Raine CS, Salzer JL, Brosnan CF, John GR. Interleukin-11 potentiates oligodendrocyte survival and maturation, and myelin formation. J Neurosci. 2006 Nov 22; 26(47):12174-85.
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Nowell MA, Richards PJ, Fielding CA, Ognjanovic S, Topley N, Williams AS, Bryant-Greenwood G, Jones SA. Regulation of pre-B cell colony-enhancing factor by STAT-3-dependent interleukin-6 trans-signaling: implications in the pathogenesis of rheumatoid arthritis. Arthritis Rheum. 2006 Jul; 54(7):2084-95.
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Spencer GC, Adunyah SE. Interleukin-11 induces rapid PKC activation and cytosolic to particulate translocation of alpha and beta PKC isoforms in human erythroleukemia K562 cells. Biochem Biophys Res Commun. 1997 Mar 06; 232(1):61-4.
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Adunyah SE, Spencer GC, Cooper RS, Rivero JA, Ceesay K. Interleukin-11 induces tyrosine phosphorylation, and c-jun and c-fos mRNA expression in human K562 and U937 cells. Ann N Y Acad Sci. 1995 Sep 07; 766:296-9.