Myelin Sheath

"Myelin Sheath" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The lipid-rich sheath surrounding AXONS in both the CENTRAL NERVOUS SYSTEMS and PERIPHERAL NERVOUS SYSTEM. The myelin sheath is an electrical insulator and allows faster and more energetically efficient conduction of impulses. The sheath is formed by the cell membranes of glial cells (SCHWANN CELLS in the peripheral and OLIGODENDROGLIA in the central nervous system). Deterioration of the sheath in DEMYELINATING DISEASES is a serious clinical problem.

Descriptor ID	D009186
MeSH Number(s)	A08.637.600.500 A08.637.800.500 A08.675.542.512.560 A08.800.800.690.500 A10.755.503 A11.284.149.165.600 A11.650.600.500 A11.650.800.500 A11.671.501.512.560 A11.671.514.553
Concept/Terms	Myelin Sheath Myelin Sheath Myelin Sheaths Sheath, Myelin Sheaths, Myelin Myelin Myelin

Below are MeSH descriptors whose meaning is more general than "Myelin Sheath".

Anatomy [A]
Nervous System [A08]
Neuroglia [A08.637]
Oligodendroglia [A08.637.600]
Myelin Sheath [A08.637.600.500]
Schwann Cells [A08.637.800]
Myelin Sheath [A08.637.800.500]
Neurons [A08.675]
Nerve Fibers [A08.675.542]
Nerve Fibers, Myelinated [A08.675.542.512]
Myelin Sheath [A08.675.542.512.560]
Peripheral Nervous System [A08.800]
Peripheral Nerves [A08.800.800]
Schwann Cells [A08.800.800.690]
Myelin Sheath [A08.800.800.690.500]
Tissues [A10]
Nerve Tissue [A10.755]
Myelin Sheath [A10.755.503]
Cells [A11]
Cellular Structures [A11.284]
Cell Membrane [A11.284.149]
Cell Membrane Structures [A11.284.149.165]
Myelin Sheath [A11.284.149.165.600]
Neuroglia [A11.650]
Oligodendroglia [A11.650.600]
Myelin Sheath [A11.650.600.500]
Schwann Cells [A11.650.800]
Myelin Sheath [A11.650.800.500]
Neurons [A11.671]
Nerve Fibers [A11.671.501]
Nerve Fibers, Myelinated [A11.671.501.512]
Myelin Sheath [A11.671.501.512.560]
Nerve Fibers, Myelinated [A11.671.514]
Myelin Sheath [A11.671.514.553]

Below are MeSH descriptors whose meaning is related to "Myelin Sheath".

Below are MeSH descriptors whose meaning is more specific than "Myelin Sheath".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Myelin Sheath" by people in this website by year, and whether "Myelin Sheath" was a major or minor topic of these publications.

Bar chart showing 27 publications over 21 distinct years, with a maximum of 4 publications in 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	1	1
1996	0	1	1
1998	0	1	1
1999	0	1	1
2000	1	0	1
2001	0	1	1
2004	1	0	1
2006	1	0	1
2007	0	1	1
2008	1	0	1
2010	0	2	2
2011	3	1	4
2012	0	1	1
2013	1	0	1
2014	1	2	3
2015	1	0	1
2016	1	0	1
2019	1	0	1
2020	1	0	1
2022	0	1	1
2023	0	1	1

Below are the most recent publications written about "Myelin Sheath" by people in Profiles.

Chuang YC, Alcantara A, Fabris G, Abderezaei J, Lu TA, Melendez-Vasquez CV, Kurt M. Myelination dictates axonal viscoelasticity. Eur J Neurosci. 2023 04; 57(8):1225-1240.

View in: PubMed
Mendiola AS, Church KA, Cardona SM, Vanegas D, Garcia SA, Macklin W, Lira SA, Ransohoff RM, Kokovay E, Lin CA, Cardona AE. Defective fractalkine-CX3CR1 signaling aggravates neuroinflammation and affects recovery from cuprizone-induced demyelination. J Neurochem. 2022 09; 162(5):430-443.

View in: PubMed
Domingues HS, Urbanski MM, Macedo-Ribeiro S, Almaktari A, Irfan A, Hernandez Y, Wang H, Relvas JB, Rubinstein B, Melendez-Vasquez CV, Pinto IM. Pushing myelination - developmental regulation of myosin expression drives oligodendrocyte morphological differentiation. J Cell Sci. 2020 08 05; 133(15).

View in: PubMed
Ban Y, Dong W, Zhang L, Zhou T, Altiti AS, Ali K, Mootoo DR, Blaho VA, Hla T, Ren Y, Ma X. Abrogation of Endogenous Glycolipid Antigen Presentation on Myelin-Laden Macrophages by D-Sphingosine Ameliorates the Pathogenesis of Experimental Autoimmune Encephalomyelitis. Front Immunol. 2019; 10:404.

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Urbanski MM, Kingsbury L, Moussouros D, Kassim I, Mehjabeen S, Paknejad N, Melendez-Vasquez CV. Myelinating glia differentiation is regulated by extracellular matrix elasticity. Sci Rep. 2016 09 20; 6:33751.

View in: PubMed
Sosa RA, Murphey C, Robinson RR, Forsthuber TG. IFN-? ameliorates autoimmune encephalomyelitis by limiting myelin lipid peroxidation. Proc Natl Acad Sci U S A. 2015 Sep 08; 112(36):E5038-47.

View in: PubMed
Lim H, Sharoukhov D, Kassim I, Zhang Y, Salzer JL, Melendez-Vasquez CV. Label-free imaging of Schwann cell myelination by third harmonic generation microscopy. Proc Natl Acad Sci U S A. 2014 Dec 16; 111(50):18025-30.

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Tanaka Y, Chambers JK, Matsuwaki T, Yamanouchi K, Nishihara M. Possible involvement of lysosomal dysfunction in pathological changes of the brain in aged progranulin-deficient mice. Acta Neuropathol Commun. 2014 Jul 15; 2:78.

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Rusielewicz T, Nam J, Damanakis E, John GR, Raine CS, Melendez-Vasquez CV. Accelerated repair of demyelinated CNS lesions in the absence of non-muscle myosin IIB. Glia. 2014 Apr; 62(4):580-91.

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Tu TW, Kim JH, Yin FQ, Jakeman LB, Song SK. The impact of myelination on axon sparing and locomotor function recovery in spinal cord injury assessed using diffusion tensor imaging. NMR Biomed. 2013 Nov; 26(11):1484-95.

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