Interleukin-4

"Interleukin-4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A soluble factor produced by activated T-LYMPHOCYTES that induces the expression of MHC CLASS II GENES and FC RECEPTORS on B-LYMPHOCYTES and causes their proliferation and differentiation. It also acts on T-lymphocytes, MAST CELLS, and several other hematopoietic lineage cells.

Descriptor ID	D015847
MeSH Number(s)	D12.644.276.374.465.186 D12.776.467.374.465.178 D23.529.374.465.186
Concept/Terms	Interleukin-4 Interleukin-4 Interleukin 4 B-Cell Growth Factor-1 B Cell Growth Factor 1 B-Cell Growth Factor-I B Cell Growth Factor I B-Cell Proliferating Factor B Cell Proliferating Factor B-Cell Stimulating Factor-1 B Cell Stimulating Factor 1 B-Cell Stimulatory Factor 1 B-Cell Stimulatory Factor-1 BCGF-1 Binetrakin BSF-1 IL-4 IL4 Mast Cell Growth Factor-2 Mast Cell Growth Factor 2 MCGF-2 B Cell Stimulatory Factor-1 B Cell Stimulatory Factor 1

Below are MeSH descriptors whose meaning is more general than "Interleukin-4".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Cytokines [D12.644.276.374]
Interleukins [D12.644.276.374.465]
Interleukin-4 [D12.644.276.374.465.186]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Cytokines [D12.776.467.374]
Interleukins [D12.776.467.374.465]
Interleukin-4 [D12.776.467.374.465.178]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
Cytokines [D23.529.374]
Interleukins [D23.529.374.465]
Interleukin-4 [D23.529.374.465.186]

Below are MeSH descriptors whose meaning is related to "Interleukin-4".

Below are MeSH descriptors whose meaning is more specific than "Interleukin-4".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Interleukin-4" by people in this website by year, and whether "Interleukin-4" was a major or minor topic of these publications.

Bar chart showing 49 publications over 20 distinct years, with a maximum of 5 publications in 1998 and 2000

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	1	1
1997	1	1	2
1998	1	4	5
2000	3	2	5
2001	1	1	2
2002	0	4	4
2003	1	1	2
2004	2	0	2
2005	0	4	4
2006	0	2	2
2007	0	2	2
2008	2	2	4
2010	1	1	2
2011	1	3	4
2012	0	1	1
2016	1	0	1
2017	1	0	1
2018	1	2	3
2019	1	0	1
2022	0	1	1

Below are the most recent publications written about "Interleukin-4" by people in Profiles.

McMillan JKP, O'Donnell P, Chang SP. Pattern recognition receptor ligand-induced differentiation of human transitional B cells. PLoS One. 2022; 17(8):e0273810.

View in: PubMed
He Z, Leong DJ, Xu L, Hardin JA, Majeska RJ, Schaffler MB, Thi MM, Yang L, Goldring MB, Cobelli NJ, Sun HB. CITED2 mediates the cross-talk between mechanical loading and IL-4 to promote chondroprotection. Ann N Y Acad Sci. 2019 04; 1442(1):128-137.

View in: PubMed
Lima MP, Costa LE, Lage DP, Dias DS, Ribeiro PAF, Machado AS, Ramos FF, Salles BCS, Fagundes MI, Carvalho GB, Franklin ML, Ch?vez-Fumagalli MA, Machado-de-?vila RA, Menezes-Souza D, Duarte MC, Teixeira AL, Gon?alves DU, Coelho EAF. Diagnostic application of recombinant Leishmania proteins and evaluation of their in vitro immunogenicity after stimulation of immune cells collected from tegumentary leishmaniasis patients and healthy individuals. Cell Immunol. 2018 12; 334:61-69.

View in: PubMed
Miller CN, Proekt I, von Moltke J, Wells KL, Rajpurkar AR, Wang H, Rattay K, Khan IS, Metzger TC, Pollack JL, Fries AC, Lwin WW, Wigton EJ, Parent AV, Kyewski B, Erle DJ, Hogquist KA, Steinmetz LM, Locksley RM, Anderson MS. Thymic tuft cells promote an IL-4-enriched medulla and shape thymocyte development. Nature. 2018 07; 559(7715):627-631.

View in: PubMed
Trivedi NH, Yu JJ, Hung CY, Doelger RP, Navara CS, Armitige LY, Seshu J, Sinai AP, Chambers JP, Guentzel MN, Arulanandam BP. Microbial co-infection alters macrophage polarization, phagosomal escape, and microbial killing. Innate Immun. 2018 04; 24(3):152-162.

View in: PubMed
Li Z, Liu F, Ma H, White PF, Yumul R, Jiang Y, Wang N, Cao X. Age exacerbates surgery-induced cognitive impairment and neuroinflammation in Sprague-Dawley rats: the role of IL-4. Brain Res. 2017 06 15; 1665:65-73.

View in: PubMed
Sharma A, Sharma P, Vishwakarma AL, Srivastava M. Functional Impairment of Murine Dendritic Cell Subsets following Infection with Infective Larval Stage 3 of Brugia malayi. Infect Immun. 2017 Jan; 85(1).

View in: PubMed
Li J, Chen XL, Shaker A, Oshima T, Shan J, Miwa H, Feng C, Zhang J. Contribution of immunomodulators to gastroesophageal reflux disease and its complications: stromal cells, interleukin 4, and adiponectin. Ann N Y Acad Sci. 2016 09; 1380(1):183-194.

View in: PubMed
Hyacinth HI, Capers PL, Archer DR, Hibbert JM. TNF-a, IFN-?, IL-10, and IL-4 levels were elevated in a murine model of human sickle cell anemia maintained on a high protein/calorie diet. Exp Biol Med (Maywood). 2014 Jan; 239(1):65-70.

View in: PubMed
Rodriguez AR, Yu JJ, Guentzel MN, Navara CS, Klose KE, Forsthuber TG, Chambers JP, Berton MT, Arulanandam BP. Mast cell TLR2 signaling is crucial for effective killing of Francisella tularensis. J Immunol. 2012 Jun 01; 188(11):5604-11.

View in: PubMed

People

Explore

Similar Concepts

Top Journals