"RNA, Messenger" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
| Descriptor ID |
D012333
|
| MeSH Number(s) |
D13.444.735.544
|
| Concept/Terms |
mRNA, Polyadenylated- mRNA, Polyadenylated
- RNA, Messenger, Polyadenylated
- Messenger RNA, Polyadenylated
- Polyadenylated Messenger RNA
- RNA, Polyadenylated Messenger
- Polyadenylated mRNA
- Poly(A)+ mRNA
|
Below are MeSH descriptors whose meaning is more general than "RNA, Messenger".
Below are MeSH descriptors whose meaning is more specific than "RNA, Messenger".
This graph shows the total number of publications written about "RNA, Messenger" by people in this website by year, and whether "RNA, Messenger" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 4 | 15 | 19 |
| 1997 | 3 | 17 | 20 |
| 1998 | 1 | 12 | 13 |
| 1999 | 5 | 14 | 19 |
| 2000 | 3 | 19 | 22 |
| 2001 | 6 | 25 | 31 |
| 2002 | 5 | 48 | 53 |
| 2003 | 4 | 49 | 53 |
| 2004 | 7 | 53 | 60 |
| 2005 | 5 | 48 | 53 |
| 2006 | 7 | 44 | 51 |
| 2007 | 3 | 48 | 51 |
| 2008 | 7 | 45 | 52 |
| 2009 | 3 | 43 | 46 |
| 2010 | 4 | 46 | 50 |
| 2011 | 9 | 44 | 53 |
| 2012 | 10 | 44 | 54 |
| 2013 | 3 | 24 | 27 |
| 2014 | 4 | 33 | 37 |
| 2015 | 9 | 32 | 41 |
| 2016 | 9 | 29 | 38 |
| 2017 | 5 | 27 | 32 |
| 2018 | 7 | 16 | 23 |
| 2019 | 6 | 12 | 18 |
| 2020 | 6 | 8 | 14 |
| 2021 | 2 | 9 | 11 |
| 2022 | 0 | 23 | 23 |
| 2023 | 1 | 15 | 16 |
| 2024 | 4 | 9 | 13 |
| 2025 | 1 | 4 | 5 |
To return to the timeline,
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Below are the most recent publications written about "RNA, Messenger" by people in Profiles.
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Tanji Y, Shimada S, Kato M, Akiyama Y, Hatano M, Tsukihara S, Igarashi Y, Kodera K, Okazaki K, Yasukawa K, Umemura K, Kamachi A, Nara A, Yamane M, Ishikawa Y, Mochizuki E, Mochida Y, Ikegami T, Ban D, Uchida S, Tanaka S. Cytokine mRNA-based therapy alleviates dendritic cell and T cell paucity to eliminate aggressive pancreatic cancer in preclinical mouse models. EBioMedicine. 2026 Mar; 125:106137.
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Mahbub M, Saha B, Goss DJ. 4E-BP1 differentially regulates translation of a subset of human mRNAs. J Biol Chem. 2026 01; 302(1):110976.
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Lloret Torres ME, Rivas Jim?nez A, Tosado Rodr?guez EL, Cardona Jordan K, Lay Rivera XX, Pe?a Se?eriz YL, Capella Mu?iz JL, Dieppa Rodr?guez M, Ruiz Bol?var DF, Gonz?lez Del Toro J, Florian Alsina JA, Col?n Rivera PA, Garcia Colon JO, Roche-Lima A, Vel?zquez-Marrero C. Comparative mRNA profile analysis from NAc of adolescent male mice after binge-like alcohol exposure eliciting deficits in context fear extinction learning. PLoS One. 2025; 20(6):e0322576.
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Verma R, Bullinger KL, Pearson A, Dhakar M, Guven E, Amini E, Simon RP, Meller R. Differential Transcript Expression and Alternative RNA Splicing Patterns to Differentiate Focal vs. Generalized-Onset Seizures. Mol Neurobiol. 2025 Oct; 62(10):13303-13317.
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Quartey JNK, Goss DJ. eIF3d and eIF4G2 mediate an alternative mechanism of cap-dependent but eIF4E-independent translation initiation. J Biol Chem. 2025 04; 301(4):108317.
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Afzal Z, Krumlauf R. Optimized smFISH Pipeline for Studying Nascent Transcription in Mouse Embryonic Tissue Samples. Methods Mol Biol. 2025; 2889:53-66.
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Orozco-Sep?lveda R, Garc?a-Morin A, Guti?rrez-Zubiate I, Rosas-Acosta G. A Vivo-Morpholino-Based Approach to Block Paralog-Specific SUMOylation. Methods Mol Biol. 2025; 2957:191-206.
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Milano SN, Bayer LV, Ko JJ, Casella CE, Bratu DP. The role of ER exit sites in maintaining P-body organization and integrity during Drosophila melanogaster oogenesis. EMBO Rep. 2025 Jan; 26(2):494-520.
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Bayer LV, Milano SN, Bratu DP. The mRNA dynamics underpinning translational control mechanisms of Drosophila melanogaster oogenesis. Biochem Soc Trans. 2024 10 30; 52(5):2087-2099.
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Varriano S, Yu A, Xu YQ, Natelson DM, Ramadei A, Kleiman FE. Estrogen receptor alpha (ERa) regulates PARN-mediated nuclear deadenylation and gene expression in breast cancer cells. RNA Biol. 2024 01; 21(1):14-23.