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Borza, Dorin-Bogdan
One or more keywords matched the following items that are connected to
Borza, Dorin-Bogdan
Item Type
Name
Academic Article
Alport alloantibodies but not Goodpasture autoantibodies induce murine glomerulonephritis: protection by quinary crosslinks locking cryptic a3(IV) collagen autoepitopes in vivo.
Academic Article
Molecular architecture of the Goodpasture autoantigen in anti-GBM nephritis.
Academic Article
The immunodominant myeloperoxidase T-cell epitope induces local cell-mediated injury in antimyeloperoxidase glomerulonephritis.
Academic Article
Proteolysis breaks tolerance toward intact a345(IV) collagen, eliciting novel anti-glomerular basement membrane autoantibodies specific for a345NC1 hexamers.
Academic Article
Quaternary epitopes of a345(IV) collagen initiate Alport post-transplant anti-GBM nephritis.
Academic Article
IgG4-restricted anti-glomerular basement membrane autoantibodies targeting quaternary epitopes of native a345(IV) collagen.
Academic Article
Quaternary organization of the goodpasture autoantigen, the alpha 3(IV) collagen chain. Sequestration of two cryptic autoepitopes by intrapromoter interactions with the alpha4 and alpha5 NC1 domains.
Academic Article
Goodpasture autoantibodies unmask cryptic epitopes by selectively dissociating autoantigen complexes lacking structural reinforcement: novel mechanisms for immune privilege and autoimmune pathogenesis.
Academic Article
Distinct epitopes for anti-glomerular basement membrane alport alloantibodies and goodpasture autoantibodies within the noncollagenous domain of alpha3(IV) collagen: a janus-faced antigen.
Academic Article
The alloantigenic sites of alpha3alpha4alpha5(IV) collagen: pathogenic X-linked alport alloantibodies target two accessible conformational epitopes in the alpha5NC1 domain.
Academic Article
A role for collagen IV cross-links in conferring immune privilege to the Goodpasture autoantigen: structural basis for the crypticity of B cell epitopes.
Concept
Epitopes
Concept
Immunodominant Epitopes
Concept
Epitopes, T-Lymphocyte
Concept
Epitopes, B-Lymphocyte
Grant
Molecular pathogenesis of anti-glomerular basement membrane nephritis
Academic Article
The goodpasture autoantigen. Mapping the major conformational epitope(s) of alpha3(IV) collagen to residues 17-31 and 127-141 of the NC1 domain.
Academic Article
The goodpasture autoantigen. Identification of multiple cryptic epitopes on the NC1 domain of the alpha3(IV) collagen chain.
Academic Article
Hydrophobic amino acid residues are critical for the immunodominant epitope of the Goodpasture autoantigen. A molecular basis for the cryptic nature of the epitope.
Academic Article
Laminin-521 is a Novel Target of Autoantibodies Associated with Lung Hemorrhage in Anti-GBM Disease.
Search Criteria
Epitopes